{"title":"牙龈炎和牙周炎患者唾液钙和钙素水平的改变","authors":"A. Primasari, Yumi Lindawati, Irma Ervina","doi":"10.9790/0853-1607011719","DOIUrl":null,"url":null,"abstract":"‘Salivary proteins have an important influence in tooth enamel remineralize associated with calcium hydroxyapatite. Statherin is the most powerful protein that binds calcium hydroxyapatite in saliva than other calcium-binding protein. Infection in gingiva and periodontal caused alteration of statherin and calcium levels. Therefore, researchers wanted to determine and to compare salivary statherin and calcium levels in gingivitis and periodontitic mainly on the Indonesian as an initial data to explore the influence of statherin and calcium in patients with gingivitis and periodontitic. By spitting method, 54 samples of whole saliva taken from gingivitis and periodontitic patients ; aged 20-50 years, doesn’t have antibiotic treatment in 3 months, no smoking, no areca chewing, not pregnant, lactating or menstruating. Statherin level measurement using ELISA method and calcium level by spectrophotometry method. Results showed mean concentration of statherin for gingivitis is 1,79 ug / ml, while periodontitics is 2,73 ug / ml. Mean concentration for calcium in gingivitis saliva is 5,31 mmol/l, and periodontitic is 0,18 mmol/l. The Spearman’s correlation test showed 2 different results from 2 groups of samples. Gingivitis group showed there is no correlation between calsium and statherin in saliva (p>0,01), but periodontitic group showed there is significant correlation between calcium and statherin in saliva (p<0,05). The result showed that, although both are the result of salivary excretion (statherin and calcium), it turns out to different infection, showed different result. These results suggest there is a different mechanism in both infection.","PeriodicalId":14489,"journal":{"name":"IOSR Journal of Dental and Medical Sciences","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2017-07-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Alteration of Salivary Calcium and Statherin Levels in Patients with Gingivitis and Periodontitis\",\"authors\":\"A. Primasari, Yumi Lindawati, Irma Ervina\",\"doi\":\"10.9790/0853-1607011719\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"‘Salivary proteins have an important influence in tooth enamel remineralize associated with calcium hydroxyapatite. Statherin is the most powerful protein that binds calcium hydroxyapatite in saliva than other calcium-binding protein. Infection in gingiva and periodontal caused alteration of statherin and calcium levels. Therefore, researchers wanted to determine and to compare salivary statherin and calcium levels in gingivitis and periodontitic mainly on the Indonesian as an initial data to explore the influence of statherin and calcium in patients with gingivitis and periodontitic. By spitting method, 54 samples of whole saliva taken from gingivitis and periodontitic patients ; aged 20-50 years, doesn’t have antibiotic treatment in 3 months, no smoking, no areca chewing, not pregnant, lactating or menstruating. Statherin level measurement using ELISA method and calcium level by spectrophotometry method. Results showed mean concentration of statherin for gingivitis is 1,79 ug / ml, while periodontitics is 2,73 ug / ml. Mean concentration for calcium in gingivitis saliva is 5,31 mmol/l, and periodontitic is 0,18 mmol/l. The Spearman’s correlation test showed 2 different results from 2 groups of samples. Gingivitis group showed there is no correlation between calsium and statherin in saliva (p>0,01), but periodontitic group showed there is significant correlation between calcium and statherin in saliva (p<0,05). The result showed that, although both are the result of salivary excretion (statherin and calcium), it turns out to different infection, showed different result. These results suggest there is a different mechanism in both infection.\",\"PeriodicalId\":14489,\"journal\":{\"name\":\"IOSR Journal of Dental and Medical Sciences\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2017-07-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"IOSR Journal of Dental and Medical Sciences\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.9790/0853-1607011719\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"IOSR Journal of Dental and Medical Sciences","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.9790/0853-1607011719","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1
摘要
唾液蛋白对牙釉质羟基磷灰石钙再矿化有重要影响。石蜡蛋白是结合唾液中羟基磷灰石钙的最强蛋白。牙龈及牙周感染可引起凝血素及钙水平的改变。因此,研究人员希望确定并比较牙龈炎和牙周病患者唾液中施他汀素和钙的水平,主要以印度尼西亚人为研究对象,作为初步数据,探讨施他汀素和钙对牙龈炎和牙周病患者的影响。采用吐痰法采集牙龈炎、牙周病患者全唾液54份;年龄20-50岁,3个月内没有抗生素治疗,不吸烟,不嚼槟榔,没有怀孕、哺乳期、月经。酶联免疫吸附法测定施他汀素水平,分光光度法测定钙水平。结果牙龈炎和牙周病患者唾液中施他汀素平均浓度分别为1.79 ug / ml和2.73 ug / ml,牙龈炎和牙周病患者唾液中钙的平均浓度分别为5.31 mmol/l和0.18 mmol/l。Spearman相关检验从两组样本中得出了两种不同的结果。牙龈炎组患者唾液中钙含量与statherin含量无相关性(p> 0.01),牙周病组患者唾液中钙含量与statherin含量有显著相关性(p< 0.05)。结果表明,虽然两者都是唾液排泄的结果(凝血素和钙),但结果表明,不同的感染,表现出不同的结果。这些结果表明,在这两种感染中存在不同的机制。
Alteration of Salivary Calcium and Statherin Levels in Patients with Gingivitis and Periodontitis
‘Salivary proteins have an important influence in tooth enamel remineralize associated with calcium hydroxyapatite. Statherin is the most powerful protein that binds calcium hydroxyapatite in saliva than other calcium-binding protein. Infection in gingiva and periodontal caused alteration of statherin and calcium levels. Therefore, researchers wanted to determine and to compare salivary statherin and calcium levels in gingivitis and periodontitic mainly on the Indonesian as an initial data to explore the influence of statherin and calcium in patients with gingivitis and periodontitic. By spitting method, 54 samples of whole saliva taken from gingivitis and periodontitic patients ; aged 20-50 years, doesn’t have antibiotic treatment in 3 months, no smoking, no areca chewing, not pregnant, lactating or menstruating. Statherin level measurement using ELISA method and calcium level by spectrophotometry method. Results showed mean concentration of statherin for gingivitis is 1,79 ug / ml, while periodontitics is 2,73 ug / ml. Mean concentration for calcium in gingivitis saliva is 5,31 mmol/l, and periodontitic is 0,18 mmol/l. The Spearman’s correlation test showed 2 different results from 2 groups of samples. Gingivitis group showed there is no correlation between calsium and statherin in saliva (p>0,01), but periodontitic group showed there is significant correlation between calcium and statherin in saliva (p<0,05). The result showed that, although both are the result of salivary excretion (statherin and calcium), it turns out to different infection, showed different result. These results suggest there is a different mechanism in both infection.