纳洛酮获取法对阿片类药物滥用、死亡率和犯罪的影响

Jennifer L. Doleac, Anit Mukherjee
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引用次数: 24

摘要

美国正在经历阿片类药物滥用的流行病。作为回应,各州实施了政策,包括增加纳洛酮的获取,这种药物在过量服用时可以挽救生命。然而,令人担忧的是,纳洛酮的广泛使用可能会通过降低过量死亡的风险,无意中导致阿片类药物的使用增加或风险增加。在本文中,我们使用交错时间的国家级纳洛酮获取法律作为一个自然实验来衡量扩大获得这种救命药物的影响。我们发现,更广泛的获取导致更多的阿片类药物相关急诊室就诊和更多的阿片类药物相关盗窃,阿片类药物相关死亡率没有可测量的净下降。我们的结论是,纳洛酮在减少危害方面具有明确而重要的作用,但如果没有补充努力,其对抗阿片类药物流行病死亡人数的能力可能有限。
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The Effects of Naloxone Access Laws on Opioid Abuse, Mortality, and Crime
The United States is experiencing an epidemic of opioid abuse. In response, states have implemented policies including increased access to naloxone, a drug that can save lives when administered during an overdose. There is a concern that widespread naloxone access may unintentionally lead to increased or riskier opioid use by reducing the risk of death from overdose, however. In this paper, we use the staggered timing of state-level naloxone access laws as a natural experiment to measure the effects of broadening access to this lifesaving drug. We find that broadened access led to more opioid-related emergency room visits and more opioid-related theft, with no net measurable reduction in opioid-related mortality. We conclude that naloxone has a clear and important role in harm reduction, yet its ability to combat the opioid epidemic’s death toll may be limited without complementary efforts.
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