Determination of the Anorexigenic Drug Sibutramine in Biologically Active Dietary Supplements

Overweight is currently a common problem in modern society. People from all over the world are in search of the easiest and fastest, as well as the most effective ways to lose weight [1].To solve this problem, people turn to various fitness routines, but most people resort to taking anorexigenic biologically active dietary supplements, as well as medications. The most effective drug on the pharmaceutical market is sibutramine. It is included in the list of potent and toxic substances and is prescription-only, which makes it difficult to buy sibutramine in a pharmacy; therefore, people often prefer herbal supplements. Sibutramine has been banned in the United States, as well as the European Union, since 2010 following the decision of the Food and Drug Administration (FDA). However, some unscrupulous manufacturers add sibutramine to anorexigenic dietary supplements to increase their effectiveness [2]. Thusthere is a need to develop analytical methods for quality control of food additives, to detect cases of fraud on the pharmaceutical market in a timely manner.