以洋甘菊(小白菊)和亚麻籽(亚麻籽)为基础的唾液替代品对老年人口干缓解作用的初步报告

Irene Morales Bozo , Ana Ortega Pinto , Gonzalo Rojas Alcayaga , Juan Pablo Aitken Saavedra , Juana Olga Salinas Flores , Claudia Lefimil Puente , Carla Lozano Moraga , José Manríquez Urbina , Blanca Urzúa Orellana
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引用次数: 4

摘要

口干症是一种常见的慢性健康状况,影响着大量的老年人。应该使用诸如唾液替代品之类的姑息治疗,但这些产品在智利市场上无法获得。目的评价一种新型洋甘菊亚麻仁唾液代用品对减轻老年人xerostomía-associated症状的疗效。方法选取40例不同来源的老年口干症患者。以洋甘菊和亚麻籽为基础的唾液替代品和以羧甲基纤维素为基础的传统人工唾液,采用双盲、随机、交叉临床试验进行测试,并在中间进行洗期。结果所有(100%)被试均有口干感,58.8%的被试有唾液粘稠感,52.9%的被试有吞咽困难感。23.5%的患者有舌感灼烧。样本中最常见的病理是动脉高血压和关节炎。临床试验结果表明,洋甘菊和亚麻籽为基础的唾液替代品可显著缓解口干感和唾液粘稠感(Wilcoxon试验P <. 05)。结论新型洋甘菊亚麻仁唾液替代品能有效缓解老年人口干症状,改善老年人的生活质量。
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Reporte preliminar sobre el efecto de un sustituto salival a base de manzanilla (Matricaria chamomilla) y linaza (Linum usitatissimum) en el alivio de la xerostomía en adultos mayores

Introduction

Xerostomia is a common chronic health condition that affects a great number of elderly people. Palliative treatment, such as salivary substitutes should be used, but these products are not accessible in the Chilean market.

Objectives

To evaluate the efficacy of a new Chamomile and linseed based saliva substitute in the reduction of xerostomía-associated symptomatology in elderly people.

Methodology

Forty elderly subjects presenting with xerostomia of various origins were selected. Chamomile and linseed based saliva substitute and a carboxymethylcellulose based conventional artificial saliva were tested using a double-blind, randomized, cross-over clinical trial with an intervining wash out period.

Results

All (100%) of subjects had a sensation of dry mouth, and 58.8% mentioned a sensation of thick saliva, 52.9% needed to drink liquids to swallow, and with a sensation of swallowing difficulty. Burning tongue sensation was recorded in 23.5% of the patients. The most frequent pathologies in the sample were arterial hypertension and arthritis. Results of the clinical tests showed that Chamomile and linseed based saliva substitute significantly relieves the sensation of dry mouth and the sensation of thick saliva (Wilcoxon test P < .05).

Conclusion

New chamomile and linseed based saliva substitute was effective in relieving xerostomia symptoms in elderly people, and could improve the quality of life of population affected by this condition.

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