Kahook双刀与小梁刀(KVT):联合白内障手术的疗效比较。

IF 1.8 Q3 OPHTHALMOLOGY Clinical ophthalmology Pub Date : 2023-01-01 DOI:10.2147/OPTH.S391527
Greg D Fliney, Eliott Kim, Miriam Sarwana, Sze Wong, Tak Yee Tania Tai, Ji Liu, Soshian Sarrafpour, Nisha Chadha, Christopher C Teng
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引用次数: 3

摘要

目的:比较Kahook Dual Blade (KDB)与trabecome联合白内障手术在降低青光眼患者眼压(IOP)和用药方面的安全性和有效性。方法:回顾性比较两家学术中心的白内障手术后KDB或小梁切除术后的眼睛。手术成功定义为IOP结果:包括KDB组90只眼和trabecome组125只眼。在POM12时,KDB组IOP平均变化为-1.9±4.9 mmHg (11.2%, P = 0.002), trabecome组IOP平均变化为-3.5±5.5 mmHg (19.1%, P < 0.001),两组间无显著差异(P = 0.20)。在POM12时,KDB组青光眼药物的平均变化为-0.8±1.5 (58%,P < 0.001), trabecome组为-0.3±1.3 (38%,P = 0.003), KDB组的药物减少幅度更大(P = 0.02)。KDB组和trabecome组的成功率分别为30%和54% (P = 0.01)。房血是最常见的并发症,KDB组的发生率为3%,trabecome组的发生率为14% (P = 0.01)。结论:KDB或trabecome联合白内障手术在降低IOP和药物负担方面是安全有效的,KDB导致更大的药物减少,而trabecome更频繁地获得成功,但前房积血的发生率增加。考虑到研究的局限性,结果是相似的。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Kahook Dual Blade versus Trabectome (KVT): Comparing Outcomes in Combination with Cataract Surgery.

Purpose: To compare the safety and efficacy of Kahook Dual Blade (KDB) versus Trabectome with cataract surgery in reducing intraocular pressure (IOP) and medications used by patients with glaucoma.

Methods: Retrospective chart review comparing eyes after KDB or Trabectome with cataract surgery at 2 academic centers. Surgical success was defined as IOP <21 mmHg with ≥20% IOP reduction at post-operative month 12 (POM12). Changes in IOP, number of glaucoma medications, and adverse events were assessed.

Results: Ninety eyes in the KDB group and 125 eyes in the Trabectome group were included. Mean changes in IOP at POM12 were -1.9 ± 4.9 mmHg (11.2%, P = 0.002) in the KDB group and -3.5 ± 5.5 mmHg (19.1%, P < 0.001) in the Trabectome group, without a significant difference between the groups (P = 0.20). Mean change in glaucoma medications at POM12 was -0.8 ± 1.5 in the KDB group (58%, P < 0.001) and -0.3 ± 1.3 (38%, P = 0.003) in the Trabectome group, with KDB having a greater decrease in medications (P = 0.02). The percentage of eyes achieving success was 30% for the KDB group and 54% for the Trabectome group (P = 0.01). Hyphema was the most common complication, with an incidence of 3% for the KDB group and 14% for the Trabectome group (P = 0.01).

Conclusion: KDB or Trabectome with cataract surgery is safe and effective at lowering IOP and medication burden, with KDB resulting in a greater reduction in medications and Trabectome more frequently achieving success with an increased incidence of hyphema. Considering the study's limitations, the outcomes were similar.

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来源期刊
Clinical ophthalmology
Clinical ophthalmology OPHTHALMOLOGY-
CiteScore
3.50
自引率
9.10%
发文量
499
审稿时长
16 weeks
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