斑点跟踪超声心动图与左心室功能正常的疑似冠状动脉病变冠状动脉造影的相关性

IF 1.2 Q3 CARDIAC & CARDIOVASCULAR SYSTEMS Journal of Cardiovascular and Thoracic Research Pub Date : 2022-01-01 DOI:10.34172/jcvtr.2022.30520
Krishan Yadav, Jayesh Prajapati, Gaurav Singh, Iva Patel, Ajay Karre, Pradeep Kumar Bansal, Vicky Garhwal
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引用次数: 1

摘要

简介:我们的研究目的是确定二维斑点跟踪超声心动图(2DSTE)在预测冠状动脉疾病(CAD)的存在和严重程度方面的诊断准确性。方法:选取经冠状动脉造影的左室功能正常(>50%)的稳定型心绞痛患者,行斑点跟踪超声心动图检查。测量每位患者的整体纵向峰值收缩应变,并将其与冠状动脉造影结果相关联。结果:CAD组男性(P=0.001)、糖尿病(P=0.01)、吸烟(P=0.01)患者数量明显高于非CAD组。与非CAD患者相比,CAD患者的整体纵向峰值收缩应变(GLPSS)显著(P=0.0001)降低。Syntax评分(SS)≥22的患者GLPSS明显低于SSP=0.0001)。平均GLPSS值随着冠状动脉病变数的增加而降低(P=0.0001)。预测CAD存在的最佳截断值-16 GLPSS灵敏度为76.7%,特异度为83.3% [AUC 0.84, PP=0.0001]。结论:2DSTE可作为一种无创筛查试验,用于预测疑似稳定型心绞痛的冠心病患者的存在、程度和严重程度。
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The correlation between speckle-tracking echocardiography and coronary angiography in suspected coronary artery disease with normal left ventricular function.

Introduction: Our study objects to determine the diagnostic accuracy of two-dimensional speckle tracking echocardiography (2DSTE) in predicting presence and severity of coronary artery disease (CAD). Methods: Patients with stable angina pectoris with normal left ventricular function (>50%) undergoing coronary angiography were enrolled and subjected to speckle tracking echocardiography. Global longitudinal peak systolic strain was measured and correlated to the results of coronary angiography for each patient. Results: Number of male (P=0.001), diabetes (P=0.01) and smoking (P=0.01) patients were significantly higher in the CAD group compared to non-CAD patients. Global longitudinal peak systolic strain (GLPSS) was significantly (P=0.0001) lower in CAD patients in comparison to non- CAD patients. GLPSS showed significantly lower in patients with Syntax score (SS)≥22 in comparison to SS<22. Cut-off value -19 for GLPSS could be used to predict the presence of significant CAD with 80.6% sensitivity and 76.5% specificity (area under curve (AUC) -0.83, P=0.0001). The mean GLPSS value decreased as the number of diseased coronary vessels increased (P=0.0001). The optimal cut-off value of -16 GLPSS with a sensitivity of 76.7% and specificity of 83.3% [AUC 0.84, P<0.0001] was found significant to predict CAD severity. Multivariate regression of GLPSS and another risk factor for predicting significant CAD, GLPSS showed OR=1.55 (CI-1.36-1.76) P=0.0001 for predicting the presence of CAD. Conclusion: 2DSTE can be used as a non-invasive screening test in predicting presence, extent and severity of significant CAD patients with suspected stable angina pectoris.

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来源期刊
Journal of Cardiovascular and Thoracic Research
Journal of Cardiovascular and Thoracic Research CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
2.00
自引率
0.00%
发文量
22
审稿时长
7 weeks
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