自闭症谱系障碍和脆性X综合征凝视回避的表型差异研究。

IF 1.9 4区医学 Q1 EDUCATION, SPECIAL Ajidd-American Journal on Intellectual and Developmental Disabilities Pub Date : 2022-11-01 DOI:10.1352/1944-7558-127.6.435

Ellen H Wilkinson, Tobias C Britton, Scott S Hall

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引用次数: 2

摘要

我们研究了自闭症谱系障碍(ASD)男孩和脆性X染色体综合征(FXS)男孩在眼睛凝视回避方面的潜在表型差异。研究1对7-18岁FXS (n = 148)、ASD (n = 168)、混合性发育障碍(MDD;N = 128)。在研究2中，患有FXS的男孩(n = 31)和患有ASD的男孩(n = 25)接受了简短的行为治疗探针，以改善眼神交流。结果显示，FXS男孩的ECAS得分明显高于ASD和MDD男孩。暴露于简短的行为治疗探针导致FXS男孩的得分显著下降，但对ASD男孩没有影响。

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Examining Phenotypic Differences in Gaze Avoidance Between Autism Spectrum Disorder and Fragile X Syndrome.

We examined potential phenotypic differences in eye gaze avoidance exhibited by boys with autism spectrum disorder (ASD) and boys with fragile X syndrome (FXS). In Study 1, the Eye Contact Avoidance Scale (ECAS) was administered to caregivers of boys aged 7-18 years with FXS (n = 148), ASD (n = 168), and mixed developmental disabilities (MDD; n = 128). In Study 2, subsets of boys with FXS (n = 31) and boys with ASD (n = 25) received a brief behavioral treatment probe to improve eye contact. Results showed that boys with FXS obtained significantly higher scores on the ECAS compared to boys with ASD and MDD. Exposure to the brief behavioral treatment probe resulted in significant decreases in scores for boys with FXS, but not for boys with ASD.

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来源期刊

Ajidd-American Journal on Intellectual and Developmental Disabilities Multiple-

CiteScore

3.10

自引率

4.80%

发文量

期刊介绍： The American Journal on Intellectual and Developmental Disabilities (Print ISSN: 1944–7515; Online ISSN: 1944–7558) is published by the American Association on Intellectual and Developmental Disabilities. It is a scientifi c, scholarly, and archival multidisciplinary journal for reporting original contributions of the highest quality to knowledge of intellectual disabilities, its causes, treatment, and prevention.