前哨淋巴结导航手术治疗早期胃癌的最新进展。

IF 4.3 3区 材料科学 Q1 ENGINEERING, ELECTRICAL & ELECTRONIC ACS Applied Electronic Materials Pub Date : 2023-01-01 DOI:10.5230/jgc.2023.23.e4
Eisuke Booka, Hiroya Takeuchi
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引用次数: 1

摘要

维持术后生活质量(QOL)的同时保证不过度治疗的治愈率是早期胃癌治疗的重要内容。早期胃癌微创保功能胃切除术有望维持术后生活质量。前哨淋巴结(SN)盆的概念对于维持早期胃癌微创保功能胃切除术的治愈性至关重要。然而,在胃癌手术后进行额外切除是困难的。因此,SN盆地理论具有重要意义。最近,韩国一项多中心随机III期试验(SENORITA试验)证明,与标准胃切除术相比,腹腔镜前哨淋巴结导航手术(LSNNS)用于胃保存的早期胃癌患者术后生活质量更好。基于治愈率不受损害的概念,LSNNS有助于提高患者的生活质量。一项多中心非随机III期试验正在日本进行,肿瘤安全性有望得到证实。LSNNS已被确定为早期胃癌患者的治疗选择,并将在未来得到广泛应用。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Recent Advances in Sentinel Node Navigation Surgery for Early Gastric Cancer.

Maintaining the postoperative quality of life (QOL) while ensuring curability without overtreatment is important in the treatment of early gastric cancer. Postoperative QOL is anticipated to be maintained through minimally invasive function-preserving gastrectomy in early gastric cancer. The concept of the sentinel lymph node (SN) basin is essential to maintain the curability of early gastric cancer using minimally invasive function-preserving gastrectomy. However, additional resection after surgery is difficult to perform in gastric cancer. Thus, the SN basin theory is important. Recently, a multicenter randomized phase III trial in South Korea (SENORITA trial) proved that laparoscopic sentinel node navigation surgery (LSNNS) for stomach preservation results in better postoperative QOL compared with standard gastrectomy in patients with early gastric cancer. LSNNS contributes to patients' QOL based on the concept that curability is not impaired. A multicenter nonrandomized phase III trial is ongoing in Japan, and oncologic safety is expected to be demonstrated. LSNNS has been established as a treatment option for selected patients with early gastric cancer, and its application will become widespread in the future.

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7.20
自引率
4.30%
发文量
567
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