{"title":"全怀恩博士纪念奖2022年。","authors":"","doi":"10.1503/jpn.230050","DOIUrl":null,"url":null,"abstract":". In a well-powered study, Steinman and colleagues showed a blunted neural fMRI response to loss, but not reward, in de-pressed individuals with anhedonia, possibly defining a sub-phenotype of depression. These changes may be linked with reduced motivation or apathy in patients that contributes to severe anhedonia. This study provides novel mechanistic insights into neural mechanisms underlying anhedonia in individuals with major depressive disorder","PeriodicalId":50073,"journal":{"name":"Journal of Psychiatry & Neuroscience","volume":"48 2","pages":"E116"},"PeriodicalIF":4.1000,"publicationDate":"2023-03-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/27/21/48-2-E116.PMC10095243.pdf","citationCount":"0","resultStr":"{\"title\":\"Dr. Francis Wayne Quan Memorial Prize 2022.\",\"authors\":\"\",\"doi\":\"10.1503/jpn.230050\",\"DOIUrl\":null,\"url\":null,\"abstract\":\". In a well-powered study, Steinman and colleagues showed a blunted neural fMRI response to loss, but not reward, in de-pressed individuals with anhedonia, possibly defining a sub-phenotype of depression. These changes may be linked with reduced motivation or apathy in patients that contributes to severe anhedonia. This study provides novel mechanistic insights into neural mechanisms underlying anhedonia in individuals with major depressive disorder\",\"PeriodicalId\":50073,\"journal\":{\"name\":\"Journal of Psychiatry & Neuroscience\",\"volume\":\"48 2\",\"pages\":\"E116\"},\"PeriodicalIF\":4.1000,\"publicationDate\":\"2023-03-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/27/21/48-2-E116.PMC10095243.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Psychiatry & Neuroscience\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.1503/jpn.230050\",\"RegionNum\":2,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"NEUROSCIENCES\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Psychiatry & Neuroscience","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.1503/jpn.230050","RegionNum":2,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"NEUROSCIENCES","Score":null,"Total":0}
. In a well-powered study, Steinman and colleagues showed a blunted neural fMRI response to loss, but not reward, in de-pressed individuals with anhedonia, possibly defining a sub-phenotype of depression. These changes may be linked with reduced motivation or apathy in patients that contributes to severe anhedonia. This study provides novel mechanistic insights into neural mechanisms underlying anhedonia in individuals with major depressive disorder
期刊介绍：
The Journal of Psychiatry & Neuroscience publishes papers at the intersection of psychiatry and neuroscience that advance our understanding of the neural mechanisms involved in the etiology and treatment of psychiatric disorders. This includes studies on patients with psychiatric disorders, healthy humans, and experimental animals as well as studies in vitro. Original research articles, including clinical trials with a mechanistic component, and review papers will be considered.
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