COVID-19患者的急性主动脉综合征

IF 0.8 Q3 MEDICINE, GENERAL & INTERNAL Archive of clinical cases Pub Date : 2023-01-01 DOI:10.22551/2023.38.1001.10239
João Campos Cunha, António José Cruz, Beatriz Madureira, Yolanda Martins, Gonçalo Sarmento
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摘要

鉴于2019冠状病毒病大流行的全球影响,了解其机制并确定最有效对策的战略至关重要。SARS-CoV-2病毒可诱导高凝状态,从而引发静脉病因性血管现象,特别是深静脉血栓形成或肺栓塞。与COVID-19相关的动脉血栓形成事件在医学文献中也有描述,尽管频率较低。在本文中,作者报告了一名66岁男子的病例,他被诊断为急性主动脉综合征,特别是主动脉弓上的壁内血栓,而他仍然感染了病毒。开始使用低质量分子肝素抗凝治疗,患者住进内科病房接受保守治疗。在一系列影像学评估中,血栓保持稳定;因此,患者出院时给予口服抗凝治疗,并在门诊随访。该病例描述了COVID-19的一种罕见且可能严重的并发症,凸显了其临床谱系的广泛性,影响肺部以外的系统。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Acute Aortic Syndrome in a patient with COVID-19.

The global effects of the COVID-19 pandemic make it of the utmost importance to comprehend its mechanisms and define strategies for the most effective approach possible. The SARS-CoV-2 virus can be responsible for the induction of a hypercoagulable state, which can trigger vascular phenomena of venous etiology, specifically deep venous thrombosis or pulmonary embolism. Arterial thrombotic events associated with COVID-19 have also been described in the medical literature, although less frequently. In this paper the authors report the case of a 66-year-old man who was diagnosed with an Acute Aortic Syndrome, specifically an intramural thrombus on the aortic arch, while he was still infected with the virus. Anticoagulation with low weight molecular heparin was initiated and the patient was admitted at the Internal Medicine ward for a conservative therapeutic approach. The thrombus remained stable on a serial imaging evaluation; therefore, the patient was discharged with oral anticoagulation with subsequent follow-up in the outpatient clinic. This case describes a rare and potentially serious complication of COVID-19, which highlights how broad its clinical spectrum can be, affecting systems other than the pulmonary.

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