硬支气管镜检查治疗肺结核后气管支气管狭窄。

IF 2.5 Q2 RESPIRATORY SYSTEM Tuberculosis and Respiratory Diseases Pub Date : 2023-10-01 Epub Date: 2023-04-27 DOI:10.4046/trd.2023.0017
Hojoong Kim
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引用次数: 0

摘要

气管支气管结核(TB)的愈合过程导致11%至42%的患者出现气管支气管纤维化,导致气道狭窄。在肺结核仍然流行的韩国,肺结核后气管支气管狭窄(PTTS)是良性气道狭窄的主要原因之一,导致进行性呼吸困难、低氧血症和经常危及生命的呼吸功能不全。30年前,刚性支气管镜的发展取代了手术管理,如今,PTTS在韩国主要通过支气管镜干预进行管理。与肺结核相似,气管支气管结核是用抗结核药物联合治疗的。在PTTS患者中,刚性支气管镜检查的指征大于美国胸科学会(ATS)3级呼吸困难。首先,在全身麻醉下,通过多种技术扩张狭窄的气道,包括球囊扩张、激光切除和探根术。然后,大多数患者需要硅胶支架来维持扩张气道的通畅性;留置1.5至2年后,支架可以取出,这显示出70%的成功率。不到10%的患者出现无死亡的急性并发症。亚组分析显示,成功移除支架与男性、年轻、基线肺功能良好和无完全单叶塌陷显著相关。总之,刚性支气管镜可以应用于PTTS患者,具有可接受的疗效和可耐受的安全性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Rigid Bronchoscopy for Post-tuberculosis Tracheobronchial Stenosis.

The healing process of tracheobronchial tuberculosis (TB) results in tracheobronchial fibrosis causing airway stenosis in 11% to 42% of patients. In Korea, where pulmonary TB is still prevalent, post-TB tracheobronchial stenosis (PTTS) is one of the main causes of benign airway stenosis causing progressive dyspnea, hypoxemia, and often life-threatening respiratory insufficiency. The development of rigid bronchoscopy replaced surgical management 30 years ago, and nowadays PTTS is mainly managed by bronchoscopic intervention in Korea. Similar to pulmonary TB, tracheobronchial TB is treated with combination of anti-TB medications. The indication of rigid bronchoscopy is more than American Thoracic Society (ATS) grade 3 dyspnea in PTTS patients. First, the narrowed airway is dilated by multiple techniques including ballooning, laser resection, and bougienation under general anesthesia. Then, most of the patients need silicone stenting to maintain the patency of dilated airway; 1.5 to 2 years after indwelling, the stent could be removed, this has shown a 70% success rate. Acute complications without mortality develop in less than 10% of patients. Subgroup analysis showed successful removal of the stent was significantly associated with male sex, young age, good baseline lung function and absence of complete one lobe collapse. In conclusion, rigid bronchoscopy could be applied to PTTS patients with acceptable efficacy and tolerable safety.

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来源期刊
CiteScore
5.30
自引率
0.00%
发文量
42
审稿时长
12 weeks
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