植物生物学中的布尔模型。

Aravind Karanam, Wouter-Jan Rappel
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摘要

信号和遗传网络是大多数生物过程的基础,通常是复杂的,包含许多高度连接的成分。对这些网络进行建模可以提供对机制的深入了解,但由于速率参数通常没有很好地定义,因此具有挑战性。布尔建模,其中组件只能采用二进制值与逻辑方程编码的连接,能够规避这些挑战,并已成为探测这些复杂网络的可行工具。在这篇综述中,我们将给出布尔建模的概述,特别强调其在植物生物学中的应用。我们回顾了布尔模型如何用于描述生物网络,然后讨论了其在植物遗传学和植物信号传导中的应用实例。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Boolean modelling in plant biology.

Signalling and genetic networks underlie most biological processes and are often complex, containing many highly connected components. Modelling these networks can provide insight into mechanisms but is challenging given that rate parameters are often not well defined. Boolean modelling, in which components can only take on a binary value with connections encoded by logic equations, is able to circumvent some of these challenges, and has emerged as a viable tool to probe these complex networks. In this review, we will give an overview of Boolean modelling, with a specific emphasis on its use in plant biology. We review how Boolean modelling can be used to describe biological networks and then discuss examples of its applications in plant genetics and plant signalling.

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