澳大利亚成人2型糖尿病患者手机短信干预的经济评价

IF 2.2 Q2 HEALTH CARE SCIENCES & SERVICES mHealth Pub Date : 2023-01-01 DOI:10.21037/mhealth-22-26
Karen A Waller, Anagha A Killedar, Susan E Furber, Eng J Tan, Alice A Gibson, Adrian E Bauman, Alison J Hayes
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摘要

背景:澳大利亚2型糖尿病患病率的上升是一个公共卫生问题,造成了重大的疾病负担和经济成本。短信项目已经被证明可以改善2型糖尿病患者的健康状况,然而,它们仍然没有得到充分利用,而且没有证据表明它们的成本效益或成本在澳大利亚的人口水平上扩大。本研究旨在确定6个月短信干预(DTEXT)改善澳大利亚成人2型糖尿病患者糖化血红蛋白(HbA1c)和自我管理行为的成本效益和成本效用。方法:对DTEXT随机对照试验进行试验内经济评价。与常规护理相比,每降低11mmol /mol(1%)的HbA1c和每增加的质量调整生命年(QALY)确定增量成本-效果比(ICERs)。成本-效益可接受曲线(CEAC)决定了干预措施在支付意愿阈值范围内具有成本效益的可能性。进行了情景分析,以确定使用当前的实施成本如何影响成本效益。结果:DTEXT干预每位参与者的成本为36澳元(24美元),每11 mmol/mol(1%)降低HbA1c的ICER为311澳元(211美元)。基于HbA1c结果,DTEXT有33%的可能性是有效和节省成本的。根据QALY结果,该干预措施的成本效益概率只有24%。情景分析表明,每位参与者的干预成本为13澳元(9美元),每11 mmol/mol(1%)降低HbA1c的增量成本效益比为151澳元(103美元),有效和节省成本的可能性为38%。结论:DTEXT成本低,具有潜在的可扩展性,但只有低到中等的有效和节省成本的可能性。进一步的研究应确定可能提高成本效益的更有针对性的方法。试验注册号:ACTRN12617000416392。
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Economic evaluation of a mobile phone text-message intervention for Australian adults with type 2 diabetes.

Background: The rising prevalence of type 2 diabetes in Australia is a public health concern, contributing to significant disease burden and economic costs. Text-message programs have been shown to improve health outcomes for people with type 2 diabetes, however they remain underutilized, and no evidence exists on their cost-effectiveness or costs of scale up to a population level in Australia. This study aimed to determine the cost-effectiveness and cost-utility of a 6-month text-message intervention (DTEXT) to improve glycated hemoglobin (HbA1c) and self-management behaviors for Australian adults with type 2 diabetes.

Methods: A within-trial economic evaluation was conducted on the DTEXT randomized controlled trial. Incremental cost-effectiveness ratios (ICERs) were determined per 11 mmol/mol (1%) reduced HbA1c and per quality adjusted life year (QALY) gained, compared to usual care. Cost-effectiveness acceptability curves (CEAC) determined the probability of the intervention being cost-effective over a range of willingness to pay thresholds. A scenario analysis was conducted to determine how cost-effectiveness was impacted by using current implementation costs.

Results: The DTEXT intervention cost AU$36 (INT$24) per participant, with an ICER of AU$311 (INT$211) per 11 mmol/mol (1%) reduced HbA1c. Based on HbA1c outcomes, DTEXT had a 33% probability of being effective and cost-saving. Based on the QALY outcomes, the intervention had only a 24% probability of being cost-effective. Scenario analysis indicated costs per participant of AU$13 (INT$9) to deliver the intervention, with a reduced incremental cost effectiveness ratio of AU$151 (INT$103) per 11 mmol/mol (1%) reduced HbA1c and a 38% probability of being effective and cost-saving.

Conclusions: DTEXT was low cost and potentially scalable, but only had a low to moderate probability of being effective and cost saving. Further research should determine more targeted approaches that may improve cost-effectiveness.

Trial registration: ACTRN12617000416392.

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