肠道微生物组与心理健康。

IF 2 Q2 NURSING Journal of Holistic Nursing Pub Date : 2024-03-01 Epub Date: 2023-04-20 DOI:10.1177/08980101231170487
Debra Rose Wilson, Leslie Binford, Shondell Hickson
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引用次数: 0

摘要

肠道微生物组在过去几年中得到了深入研究,并可能成为治疗精神疾病的目标。消化系统中数以万计的细菌与大脑、免疫功能和内分泌途径共同发挥作用。肠道微生物群生态系统介导着人类与环境之间的互动,因此将其纳入整体护理至关重要。肠道微生物群的正常平衡会随着饮食、抗生素和其他药物、压力、癌症治疗、地理和环境以及当前疾病而发生变化。当微生物群受到挑战时,"菌群失调 "状态会导致所需的神经递质(如血清素和多巴胺)分泌不足。研究表明,菌群失调与炎症反应系统之间存在联系,而众所周知,炎症反应系统会导致抑郁症、焦虑症和精神分裂症。了解肠道微生物组的作用对整体护理非常有益,它为预防、治疗或减轻精神疾病的症状以及改善一般免疫功能提供了一种新的工具。这种无害的心理健康整体方法正在成为一种重要的循证方法。
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The Gut Microbiome and Mental Health.

The gut microbiome has been well researched in the past few years and may be a target for treating mental illness. Trillions of bacteria in the digestive system work with the brain, immune function, and endocrine pathways. This gut microbiome ecosystem mediates the interaction between the human being and the environment making its inclusion in holistic nursing essential. Changes in normal balance of the gut microbiome occur with diet, antibiotics and other medications, stress, cancer treatment, geography and environment, and current illnesses. When the microbiome is challenged a "dysbiotic" state leads to inadequate production of needed neurotransmitters such as serotonin and dopamine. Research has shown links between the dysbiosis, and the inflammatory response system that are known to contribute to depression, anxiety, and schizophrenia. Understanding the role of the gut microbiome can be beneficial to holistic nurses, providing a new tool to prevent, treat, or reduce symptoms of mental illness and improve general immune function. This innocuous holistic approach to mental wellness is becoming an important evidenced-based approach.

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来源期刊
CiteScore
4.30
自引率
10.00%
发文量
39
期刊介绍: Manuscripts are solicited that deal with the processes of knowledge development and application including research, concept analysis and theory development, practical applications of research and theory, clinical case studies and analysis, practice applications in general, educational approaches and evaluation, and aesthetic expressions of holistic knowledge. While the journal seeks to support work grounded in evidence, the editorial philosophy suggests that there are many diverse sources of “evidence” beyond the realm of what is called “empirical” and that many methods are appropriate for discovering evidence and generating knowledge.
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