骨折愈合-骨科:从基础科学到临床应用。

Joey P Johnson, Jaimo Ahn, Douglas R Dirschl, John J Wixted, Andrew R Evans
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引用次数: 0

摘要

骨科作为一个领域和专业,从根本上讲是与各种形式的肌肉骨骼疾病的治疗有关。我们对损伤引起的肌肉骨骼病理的细胞机制的集体理解不断发展,为发展骨科治疗以改善护理提供了新的机会。从对细胞病理学的理解到成功临床治疗的发展,这是一条漫长的道路,本文建议讨论在骨科中实现转化治疗的一些挑战。本文将重点关注临床医生在寻求将有希望的治疗方法引入临床实践时可能面临的挑战,以及提高转化工作成功的策略。
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Fracture healing-orthobiologics: from basic science to clinical application.

Orthopaedics as a field and a profession is fundamentally concerned with the treatment of musculoskeletal disease, in all of its many forms. Our collective understanding of the cellular mechanisms underlying musculoskeletal pathology resulting from injury continues to evolve, opening novel opportunities to develop orthobiologic treatments to improve care. It is a long path to move from an understanding of cellular pathology to development of successful clinical treatment, and this article proposes to discuss some of the challenges to achieving translational therapies in orthopaedics. The article will focus on challenges that clinicians will likely face in seeking to bring promising treatments forward to clinical practice and strategies for improving success in translational efforts.

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