建立COVID-19和疫苗接种期间全血细胞计数参考区间。

IF 3.8 3区 医学 Q1 MEDICAL LABORATORY TECHNOLOGY Biochemia Medica Pub Date : 2023-06-15 DOI:10.11613/BM.2023.020701
Claudia Mendieta-Gutiérrez, Selene Chávez-González, Brenda Ivonne Rodríguez-Romero, Jazmín Anahí Sánchez-Garrido, Arturo Figueroa-Gómez, Jesús Bernabé Licona-Vela, Arturo Cuauhtémoc Juárez-Pérez, Alejandro Cabello-López, Guadalupe Aguilar-Madrid, Carmina Jiménez-Ramírez
{"title":"建立COVID-19和疫苗接种期间全血细胞计数参考区间。","authors":"Claudia Mendieta-Gutiérrez,&nbsp;Selene Chávez-González,&nbsp;Brenda Ivonne Rodríguez-Romero,&nbsp;Jazmín Anahí Sánchez-Garrido,&nbsp;Arturo Figueroa-Gómez,&nbsp;Jesús Bernabé Licona-Vela,&nbsp;Arturo Cuauhtémoc Juárez-Pérez,&nbsp;Alejandro Cabello-López,&nbsp;Guadalupe Aguilar-Madrid,&nbsp;Carmina Jiménez-Ramírez","doi":"10.11613/BM.2023.020701","DOIUrl":null,"url":null,"abstract":"<p><strong>Introduction: </strong>COVID-19 and vaccination may affect some parameters of the complete blood count (CBC). The aim of this study was to determine reference intervals (RI) of CBC in healthy population with different COVID-19 and vaccination backgrounds and compare them with those established previously.</p><p><strong>Materials and methods: </strong>A cross-sectional study was conducted in donors who attended the Traumatology Hospital \"Dr. Victorio de la Fuente Narváez\" (HTVFN) from June to September 2021. Reference intervals were established using the non-parametric method on Sysmex XN-1000. For differences between groups with different COVID-19 and vaccination backgrounds, non-parametric tests were used.</p><p><strong>Results: </strong>The RI were established in 156 men and 128 women. Haemoglobin (Hb), haematocrit (Hct), red blood cells (RBC), platelets (Plt), mean platelets volume (MPV), monocytes and relative neutrophils were higher in men than women (P < 0.001). The percentiles of Hb, Hct, RBC, MPV and relative monocytes showed higher values; Plt, white blood cells (WBC), lymphocytes, monocytes, neutrophils, eosinophils and absolute basophils, the 2.5th was higher and the 97.5th was lower; for lymphocytes and relative neutrophils, both percentiles had a trend toward lower values, compared to previous RI. Differences between groups with different COVID-19 and vaccination backgrounds, in lymphocytes (P = 0.038), neutrophils (P = 0.017) and eosinophils (P = 0.018) in men; Hct (P = 0.014), RDW (P = 0.023) in women and MPV (P = 0.001) in both, were not considered pathological.</p><p><strong>Conclusions: </strong>The RI for the CBC were established in a Mestizo-Mexican population with different COVID-19 and vaccination backgrounds, so should be updated and validated in different hospitals close to the HTVFN that use the same analyser.</p>","PeriodicalId":9021,"journal":{"name":"Biochemia Medica","volume":null,"pages":null},"PeriodicalIF":3.8000,"publicationDate":"2023-06-15","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152613/pdf/","citationCount":"0","resultStr":"{\"title\":\"Establishment of reference intervals for complete blood count in times of COVID-19 and vaccination.\",\"authors\":\"Claudia Mendieta-Gutiérrez,&nbsp;Selene Chávez-González,&nbsp;Brenda Ivonne Rodríguez-Romero,&nbsp;Jazmín Anahí Sánchez-Garrido,&nbsp;Arturo Figueroa-Gómez,&nbsp;Jesús Bernabé Licona-Vela,&nbsp;Arturo Cuauhtémoc Juárez-Pérez,&nbsp;Alejandro Cabello-López,&nbsp;Guadalupe Aguilar-Madrid,&nbsp;Carmina Jiménez-Ramírez\",\"doi\":\"10.11613/BM.2023.020701\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Introduction: </strong>COVID-19 and vaccination may affect some parameters of the complete blood count (CBC). The aim of this study was to determine reference intervals (RI) of CBC in healthy population with different COVID-19 and vaccination backgrounds and compare them with those established previously.</p><p><strong>Materials and methods: </strong>A cross-sectional study was conducted in donors who attended the Traumatology Hospital \\\"Dr. Victorio de la Fuente Narváez\\\" (HTVFN) from June to September 2021. Reference intervals were established using the non-parametric method on Sysmex XN-1000. For differences between groups with different COVID-19 and vaccination backgrounds, non-parametric tests were used.</p><p><strong>Results: </strong>The RI were established in 156 men and 128 women. Haemoglobin (Hb), haematocrit (Hct), red blood cells (RBC), platelets (Plt), mean platelets volume (MPV), monocytes and relative neutrophils were higher in men than women (P < 0.001). The percentiles of Hb, Hct, RBC, MPV and relative monocytes showed higher values; Plt, white blood cells (WBC), lymphocytes, monocytes, neutrophils, eosinophils and absolute basophils, the 2.5th was higher and the 97.5th was lower; for lymphocytes and relative neutrophils, both percentiles had a trend toward lower values, compared to previous RI. Differences between groups with different COVID-19 and vaccination backgrounds, in lymphocytes (P = 0.038), neutrophils (P = 0.017) and eosinophils (P = 0.018) in men; Hct (P = 0.014), RDW (P = 0.023) in women and MPV (P = 0.001) in both, were not considered pathological.</p><p><strong>Conclusions: </strong>The RI for the CBC were established in a Mestizo-Mexican population with different COVID-19 and vaccination backgrounds, so should be updated and validated in different hospitals close to the HTVFN that use the same analyser.</p>\",\"PeriodicalId\":9021,\"journal\":{\"name\":\"Biochemia Medica\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":3.8000,\"publicationDate\":\"2023-06-15\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://www.ncbi.nlm.nih.gov/pmc/articles/PMC10152613/pdf/\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Biochemia Medica\",\"FirstCategoryId\":\"3\",\"ListUrlMain\":\"https://doi.org/10.11613/BM.2023.020701\",\"RegionNum\":3,\"RegionCategory\":\"医学\",\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q1\",\"JCRName\":\"MEDICAL LABORATORY TECHNOLOGY\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Biochemia Medica","FirstCategoryId":"3","ListUrlMain":"https://doi.org/10.11613/BM.2023.020701","RegionNum":3,"RegionCategory":"医学","ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q1","JCRName":"MEDICAL LABORATORY TECHNOLOGY","Score":null,"Total":0}
引用次数: 0

摘要

导语:COVID-19和疫苗接种可能影响全血细胞计数(CBC)的某些参数。本研究的目的是确定不同COVID-19和疫苗接种背景的健康人群CBC的参考区间(RI),并将其与先前建立的参考区间进行比较。材料和方法:对2021年6月至9月在创伤医院“Dr. Victorio de la Fuente Narváez”(HTVFN)就诊的供体进行了横断面研究。采用非参数法在Sysmex XN-1000上建立参考区间。对于不同COVID-19和疫苗接种背景的组间差异,采用非参数检验。结果:在156名男性和128名女性中建立了RI。血红蛋白(Hb)、红细胞压积(Hct)、红细胞(RBC)、血小板(Plt)、平均血小板体积(MPV)、单核细胞和相对中性粒细胞男性高于女性(P < 0.001)。Hb、Hct、RBC、MPV和相对单核细胞的百分位数较高;白细胞(WBC)、淋巴细胞、单核细胞、中性粒细胞、嗜酸性粒细胞和绝对嗜碱性粒细胞,2.5较高,97.5较低;对于淋巴细胞和相对中性粒细胞,与先前的RI相比,这两个百分位数都有降低的趋势。不同COVID-19和疫苗接种背景组男性淋巴细胞(P = 0.038)、中性粒细胞(P = 0.017)和嗜酸性粒细胞(P = 0.018)的差异;女性的Hct (P = 0.014)、RDW (P = 0.023)和MPV (P = 0.001)不被认为是病理。结论:CBC的RI是在具有不同COVID-19和疫苗接种背景的墨西哥混血人群中建立的,因此应在靠近HTVFN的不同医院使用相同的分析仪进行更新和验证。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Establishment of reference intervals for complete blood count in times of COVID-19 and vaccination.

Introduction: COVID-19 and vaccination may affect some parameters of the complete blood count (CBC). The aim of this study was to determine reference intervals (RI) of CBC in healthy population with different COVID-19 and vaccination backgrounds and compare them with those established previously.

Materials and methods: A cross-sectional study was conducted in donors who attended the Traumatology Hospital "Dr. Victorio de la Fuente Narváez" (HTVFN) from June to September 2021. Reference intervals were established using the non-parametric method on Sysmex XN-1000. For differences between groups with different COVID-19 and vaccination backgrounds, non-parametric tests were used.

Results: The RI were established in 156 men and 128 women. Haemoglobin (Hb), haematocrit (Hct), red blood cells (RBC), platelets (Plt), mean platelets volume (MPV), monocytes and relative neutrophils were higher in men than women (P < 0.001). The percentiles of Hb, Hct, RBC, MPV and relative monocytes showed higher values; Plt, white blood cells (WBC), lymphocytes, monocytes, neutrophils, eosinophils and absolute basophils, the 2.5th was higher and the 97.5th was lower; for lymphocytes and relative neutrophils, both percentiles had a trend toward lower values, compared to previous RI. Differences between groups with different COVID-19 and vaccination backgrounds, in lymphocytes (P = 0.038), neutrophils (P = 0.017) and eosinophils (P = 0.018) in men; Hct (P = 0.014), RDW (P = 0.023) in women and MPV (P = 0.001) in both, were not considered pathological.

Conclusions: The RI for the CBC were established in a Mestizo-Mexican population with different COVID-19 and vaccination backgrounds, so should be updated and validated in different hospitals close to the HTVFN that use the same analyser.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Biochemia Medica
Biochemia Medica 医学-医学实验技术
CiteScore
5.50
自引率
3.00%
发文量
70
审稿时长
>12 weeks
期刊介绍: Biochemia Medica is the official peer-reviewed journal of the Croatian Society of Medical Biochemistry and Laboratory Medicine. Journal provides a wide coverage of research in all aspects of clinical chemistry and laboratory medicine. Following categories fit into the scope of the Journal: general clinical chemistry, haematology and haemostasis, molecular diagnostics and endocrinology. Development, validation and verification of analytical techniques and methods applicable to clinical chemistry and laboratory medicine are welcome as well as studies dealing with laboratory organization, automation and quality control. Journal publishes on a regular basis educative preanalytical case reports (Preanalytical mysteries), articles dealing with applied biostatistics (Lessons in biostatistics) and research integrity (Research integrity corner).
期刊最新文献
Quality assurance of add-on testing in plasma samples: stability limit for 29 biochemical analytes Two cases with discrepancy in the quantitative cytological assessment of cerebrospinal fluid in neonatal samples using light microscopy in comparison with Sysmex XN-1000 Common P-glycoprotein () polymorphisms do not seem to be associated with the risk of rivaroxaban-related bleeding events: Preliminary data CLSI-based verification and establishment of reference intervals for common biochemical assays in Croatian newborns Prediction interval: A powerful statistical tool for monitoring patients and analytical systems
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1