酒精消费对男性生殖器硬化地衣的潜在保护作用:一项病例对照研究。

IF 1.8 Q3 UROLOGY & NEPHROLOGY Advances in Urology Pub Date : 2023-01-01 DOI:10.1155/2023/7208312
Joey El Khoury, Jessica Andraos, Anthony Kanbar, Rami Halabi, Serge Assaf, Anthony Mina, Sabine El Breidi, Charbel Dabal, Charbel El Hachem, Rodrigue Saad, Antoine Kassis, Maher Abdessater, Raghid El Khoury
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引用次数: 1

摘要

材料与方法:采用巢式病例对照研究设计。纳入的受试者为2010年1月至2020年12月在我校医院行包皮环切术的成年男性患者,病理确诊为LSc。病例按年龄与对照按1:1的比例匹配,所有患者均行包皮环切术,病理报告阴性。数据收集包括社会人口学、行为、既往病史和家族史特征。结果:共纳入94例患者。LSc男性组平均年龄49.81(±22.92)岁。两组比较在社会人口学特征(年龄和BMI)上没有发现显著差异。与饮酒相反,吸烟不能预测LSc,我们发现饮酒是防止LSc出现的保护因素(p=0.027)。患有LSc的男性患糖尿病(p=0.021)和高血压(p=0.004)的几率明显更高。没有发现LSc与主诉、LSc家族史和既往阴茎创伤之间的联系。结论:在这项研究中,我们能够比较47例被诊断为LSc的包皮环切术患者和对照组之间的多个变量。我们发现LSc患者患糖尿病和高血压的比例更高。酒精消费的潜在保护作用将在未来更大的样本量和更高的统计能力的项目中进行探索。
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A Potential Protective Effect of Alcohol Consumption in Male Genital Lichen Sclerosus: A Case-Control Study.

Materials and methods: A nested case-control study design was chosen. Subjects enrolled were adult male patients who had a circumcision between January 2010 and December 2020 at our university hospital, with a confirmed LSc diagnosis on pathology. Cases were matched with controls by age with a ratio of 1 : 1, all of whom were circumcised and had a negative pathology report. Data collection consisted of sociodemographic, behavioral, and past medical and familial history characteristics.

Results: A total of 94 patients were enrolled. The mean age was 49.81 (±22.92) in the group of men with LSc. No significant differences in sociodemographic characteristics (age and BMI) were found between the two compared groups. Smoking cannot predict LSc as opposed to alcohol consumption, which we found to be a protective factor against the appearance of LSc (p=0.027). Men with LSc had significantly higher rates of diabetes (p=0.021) and hypertension (p=0.004). No associations were found between LSc and the presenting chief complaints, family history of LSc, and past penile trauma.

Conclusion: In this study, we were able to compare multiple variables between 47 circumcised patients diagnosed with LSc and a control group. We found that LSc patients showed higher rates of diabetes and hypertension. A potential protective effect of alcohol consumption is to be explored in future projects with bigger sample sizes and higher statistical powers.

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来源期刊
Advances in Urology
Advances in Urology UROLOGY & NEPHROLOGY-
CiteScore
2.90
自引率
0.00%
发文量
17
审稿时长
15 weeks
期刊介绍: Advances in Urology is a peer-reviewed, open access journal that publishes state-of-the-art reviews and original research papers of wide interest in all fields of urology. The journal strives to provide publication of important manuscripts to the widest possible audience worldwide, without the constraints of expensive, hard-to-access, traditional bound journals. Advances in Urology is designed to improve publication access of both well-established urologic scientists and less well-established writers, by allowing interested scientists worldwide to participate fully.
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