新冠肺炎后间质性肺异常的发病率和管理。

IF 1.1 Q4 RESPIRATORY SYSTEM Current pulmonology reports Pub Date : 2023-01-01 Epub Date: 2023-04-11 DOI:10.1007/s13665-023-00307-y
Mark Robertshaw, Corey D Kershaw
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引用次数: 1

摘要

综述目的:本综述旨在总结现有文献,以确定新冠肺炎住院后持续性间质性肺异常(ILAs)的发病率和危险因素。对目前和未来的治疗方案进行了审查,以帮助肺科医生照顾这一迅速增长的患者群体。最近的发现:统计模型表明,在所有新冠肺炎住院患者中,11.7%的患者在长期随访成像中具有不可逆的纤维化特征。摘要:现有证据表明,高达30%的患者在新冠肺炎住院后患有ILA。大多数患者的放射学异常得到改善或解决。然而,据估计,这些患者中有多达三分之一具有不可逆的纤维化特征。抗纤维化药物影响的临床试验正在进行中。由于美国每周仍有数千人因新冠肺炎住院,新冠肺炎后ILA的管理将成为肺科医生的常见问题。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Post COVID Interstitial Lung Abnormalities-Incidence and Management.

Purpose of review: This review aims to summarize the available literature to identify the incidence and risk factors for persistent interstitial lung abnormalities (ILAs) following hospitalization for COVID-19. The current and prospective treatment options are reviewed in an effort to help pulmonary practitioners care for this burgeoning patient population.

Recent findings: Statistical modeling suggests that 11.7% of all patients hospitalized with COVID-19 have irreversible fibrotic features on long-term follow-up imaging.

Summary: The available evidence suggests that up to 30% of patients have ILAs following COVID-19 hospitalization. The radiographic abnormalities improve or resolve in a majority of these patients. However, estimates suggest that up to one-third of these patients have irreversible fibrotic features. Clinical trials of the impact of anti-fibrotic agents are ongoing. As there continue to be thousands of COVID-19 hospitalizations in the USA each week, the management of post-COVID ILAs will become a common problem for the pulmonary practitioner.

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