循环镁作为心源性猝死的潜在风险分层工具:一项系统综述

Edward Davis, Bernard C Fernando, Louis Fabio Jonathan Jusni, Kevin R Hendryan, Rexel Kuatama, Denio A Ridjab
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引用次数: 0

摘要

背景:心源性猝死(SCD)是心血管死亡的主要原因之一,占全世界死亡人数的15-20%。目前使用降低左室射血分数的分层策略不足以对SCD的风险进行分层,特别是在普通人群中。近年来,越来越多的证据表明镁具有抗心律失常的特性。在这篇系统综述中,作者旨在确定循环镁作为SCD的潜在风险分层工具。方法:本系统评价基于系统评价和荟萃分析的首选报告项目(PRISMA),于2021年7月进行,来源包括Google Scholar、PubMed、Science Direct、EBSCO Medline和ProQuest。结果:本综述共纳入6项研究。在普通人群中进行的三项研究一致表明,高循环镁人群患SCD的风险较低。在心脏重症监护病房(ICCU)患者中,循环镁水平与SCD风险之间没有关联,而在充血性心力衰竭(CHF)患者中,结果则相互矛盾。结论:高循环镁可能有潜力作为SCD的风险分层工具,特别是在普通人群中。然而,需要进一步的研究来支持这一证据。
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Circulating magnesium as a potential risk stratification tool for sudden cardiac death: a systematic review.

Background: Sudden cardiac death (SCD) is one of the main causes of cardiovascular mortality and accounts for 15-20% of deaths worldwide. The current stratification strategy using depressed left ventricular ejection fraction is insufficient to stratify the risk of SCD, especially in the general population. In recent years, there has been increasing evidence showing the antiarrhythmic properties of magnesium. In this systematic review, the authors aim to determine circulating magnesium as a potential risk stratification tool for SCD.

Methods: This systematic review was based on Preferred Reporting Items for Systematic Reviews and Meta-Analyses (PRISMA) and was conducted in July 2021 with sources from Google Scholar, PubMed, Science Direct, EBSCO Medline, and ProQuest.

Results: A total of six studies were included in this review. Three studies conducted in the general population consistently showed lower risk of SCD in populations with high circulating magnesium. There was no association between circulating magnesium level and risk of SCD in intensive cardiac care unit (ICCU) patients, whilst the results were conflicting in congestive heart failure (CHF) patients.

Conclusion: High circulating magnesium might have the potential to be utilized as a risk stratification tool for SCD, especially in the general population. However, further study is needed to support this evidence.

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来源期刊
Herzschrittmachertherapie und Elektrophysiologie
Herzschrittmachertherapie und Elektrophysiologie Medicine-Cardiology and Cardiovascular Medicine
CiteScore
1.10
自引率
0.00%
发文量
76
期刊介绍: Mit wissenschaftlichen Original- und Übersichtsarbeiten, Berichten über moderne Operationstechniken und experimentelle Methoden ist die Zeitschrift Herzschrittmachertherapie + Elektrophysiologie ein Diskussionsforum für Themen wie: - Zelluläre Elektrophysiologie - Theoretische Elektrophysiologie - Klinische Elektrophysiologie - Angewandte Herzschrittmachertherapie - Bradykarde und tachykarde Herzrhythmusstörungen - Plötzlicher Herztod und Risikostratifikation - Elektrokardiographie - Elektromedizinische Technologie - Experimentelle und klinische Pharmakologie - Herzchirurgie bei Herzrhythmusstörungen Mitteilungen der Arbeitsgruppen Herzschrittmacher und Arrhythmie der Deutschen Gesellschaft für Kardiologie - Herz und Kreislaufforschung e.V. (DGK) sowie Stellungnahmen und praktische Hinweise runden das breite Spektrum dieser Zeitschrift ab. Interessensgebiete: Kardiologie, Herzschrittmachertherapie, Herzschrittmachertechnologie, klinische Elektrophysiologie
期刊最新文献
[Controversies in rhythmology]. [Atrial fibrillation in combination with severe mitral regurgitation : Which should be treated first, the atrial fibrillation or the mitral valve?] [Initial ablation of atrial fibrillation-Is pulmonary vein isolation sufficient? : Pro and contra]. [(LV)EF is a poor predictor of sudden cardiac death : Pro/Contra]. Erratum zu: Herzrhythmusstörungen bei Erwachsenen mit angeborenen Herzfehlern.
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