果糖胺对监测糖尿病治疗的补偿和效果的重要性。

IF 4.1 Q2 ENDOCRINOLOGY & METABOLISM Journal of Diabetes Science and Technology Pub Date : 2024-11-01 Epub Date: 2023-06-06 DOI:10.1177/19322968231174921
Natalya Akhetova, Zhangentkhan Abylaiuly, Svetlana Bolshakova
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引用次数: 0

摘要

背景:使用果糖胺评估血糖控制情况是诊断学中的一个新步骤,近年来科学界对此进行了积极的讨论。因此,这项工作的目的是研究表面上健康的人和糖尿病(DM)患者体内果糖胺的平均水平,以及在评估住院七至十天的高血糖患者的住院治疗效果时使用果糖胺的可能性:这项研究工作于 2020 年至 2022 年期间在哈萨克斯坦共和国阿拉木图市内分泌科开展。这项工作包括对之前检查过的患者进行回顾性分析和前瞻性阶段。统计评估采用可靠性系数、置信区间和正态性检验标准的计算方法。本文首次分析了相应地区健康人的果糖胺水平,并发现了该指标与糖化血红蛋白水平之间的相关性:还研究了在静止条件下七至十天内治疗 2 型糖尿病(根据治疗方案)的效果,从而可以判断处方疗法的有效性:这些结果将有助于及早发现处方疗法的不合理性,这对于正确管理这种病症的患者并将可能出现的并发症降至最低尤为重要。
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The Importance of Fructosamine for Monitoring the Compensation and Effectiveness of Diabetes Treatment.

Background: The use of fructosamine to assess the glycemic control represents a new step in diagnostics, and it has been accompanied by the active scientific discussion in recent years. That is why the purpose of this work is to study the average level of fructosamine in apparently healthy individuals and individuals with diabetes mellitus (DM), as well as the possibility to use it when evaluating the effectiveness of inpatient treatment of patients with hyperglycemia on the seven to ten days of hospitalization.

Methods: This research work was carried out in Alma-Ata, Republic of Kazakhstan, based on the endocrinology department in the period from 2020 to 2022. The work consists of a retrospective analysis of previously examined patients and a prospective stage. The statistical evaluation was carried out with the calculation of reliability coefficient, confidence interval, and criteria for testing for normality. The level of fructosamine in healthy individuals in the corresponding region was analyzed in this article for the first time, and the correlation between this indicator and the level of glycated hemoglobin was found.

Results: The effectiveness of treatment of the Type 2 DM (according to the treatment protocol) has also been studied in stationary conditions for the seven to ten days, which makes it possible to judge the effectiveness of the prescribed therapy.

Conclusions: These results will allow identifying the irrationality of the prescribed therapy at an early stage, which is especially important for the correct management of patients with this pathology, and minimizing the possible complications.

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来源期刊
Journal of Diabetes Science and Technology
Journal of Diabetes Science and Technology Medicine-Internal Medicine
CiteScore
7.50
自引率
12.00%
发文量
148
期刊介绍: The Journal of Diabetes Science and Technology (JDST) is a bi-monthly, peer-reviewed scientific journal published by the Diabetes Technology Society. JDST covers scientific and clinical aspects of diabetes technology including glucose monitoring, insulin and metabolic peptide delivery, the artificial pancreas, digital health, precision medicine, social media, cybersecurity, software for modeling, physiologic monitoring, technology for managing obesity, and diagnostic tests of glycation. The journal also covers the development and use of mobile applications and wireless communication, as well as bioengineered tools such as MEMS, new biomaterials, and nanotechnology to develop new sensors. Articles in JDST cover both basic research and clinical applications of technologies being developed to help people with diabetes.
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