人工尿对双J型支架结痂的评价。

IF 1.1 4区 医学 Q3 UROLOGY & NEPHROLOGY Clinical nephrology Pub Date : 2023-06-01 DOI:10.5414/CN111038
Seung Bae Lee, Se-Hyun Park, Hyoung-Ho Kim, Chang Je Lee, Sang Won Seon, Yasutaka Baba, Kyung-Wuk Kim, Young Ho Choi
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引用次数: 0

摘要

目的:探讨人工尿液对双J型支架结痂的影响。材料和方法:本研究建立了一个含有人工尿液的静态泌尿系统,共使用45个djs来评估结痂的形成。三组15个DJSs分别进行4周、8周和14周的测试。采用x射线粉末衍射(XRD)、电感耦合等离子体分光光度计(ICP)和扫描电子显微镜(SEM)等方法分析了DJSs在数周内结壳的形成情况。数据分析采用R语言进行统计分析和不确定度检验。结果:ICP分析了尿路结石和结痂的主要成分钙和镁的重量,结果显示14周时最重。测量DJSs外表面结皮面积发现,无论实验时间长短,支架底部结皮面积大于支架顶部结皮面积(近端≤41,099µm2,远端≤183,259µm2)。在DJSs的侧孔周围发生结壳,随着时间的推移,结壳变大以填满侧孔。结论:结痂点主要分布在dj底部及侧孔周围。这些结果表明,通过改变位于气囊和侧孔附近的DJSs的形状,可以提高DJSs的性能。
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Evaluation of encrustation of double J stents with artificial urine.

Purpose: To evaluate the formation of encrustation on double J stents (DJSs) using artificial urine.

Materials and methods: In this study, a static urinary system containing artificial urine was created, and a total of 45 DJSs were used to evaluate the formation of encrustation. Three groups of 15 DJSs were tested for 4, 8, or 14 weeks. The formation of encrustation on the DJSs over the weeks was analyzed using methods including X-ray powder diffraction (XRD), inductively coupled plasma spectrophotometer (ICP), and scanning electron microscope (SEM). Statistical analysis and the uncertainty test were used for data analysis using R language.

Results: The ICP analyzed the weight of the calcium and magnesium, which are the major components of urinary stones and encrustation, and showed that it was the heaviest at 14 weeks. Measurement of the area of encrustation on the outer surface of the DJSs revealed that the encrustation area at the bottom of the stent was greater than that at the top of the stent, regardless of the experimental period (proximal part: ≤ 41,099 µm2, distal part: ≤ 183,259 µm2). Encrustation occurred around the side holes of DJSs and became bigger over time to fill up the side holes.

Conclusion: Encrustation spots included the bottom zone of the DJS and around the side holes. These results indicate that the performance of DJSs would be improved by modifying the shape of DJSs located near the bladder and side holes.

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来源期刊
Clinical nephrology
Clinical nephrology 医学-泌尿学与肾脏学
CiteScore
2.10
自引率
9.10%
发文量
138
审稿时长
4-8 weeks
期刊介绍: Clinical Nephrology appears monthly and publishes manuscripts containing original material with emphasis on the following topics: prophylaxis, pathophysiology, immunology, diagnosis, therapy, experimental approaches and dialysis and transplantation.
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