冠状病毒感染患者的细菌并发症,新的诊断和治疗可能性。

Q3 Medicine Przeglad epidemiologiczny Pub Date : 2023-01-01 DOI:10.32394/pe.77.06
Marceli Łukaszewski, Kamil Nelke
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引用次数: 0

摘要

我们报告了一位在COVID-19爆发期间患上肺炎的年轻患者的病例。病程以累及肺间质组织为不典型细菌性感染,感染标志物图可提示SARS-CoV-2。入院时采用PCR检测,结果均为阴性。由于该疾病的随访不典型,提示SARS病程严重,因此对BAL收集的材料进行了BIOFIRE®FILMARRAY®Pneumonia plus Panel (biomsamrieux)的PCR检测。发现嗜肺军团菌和冠状病毒遗传物质。我们的结论是,在所描述的病例中,有一种细菌共感染,由病毒感染铺就。这两例肺炎的相似的放射学图像,以及血液中相似的感染反应,非典型感染的特异性,可能会对鉴别诊断造成问题。该研究能够确认肺炎的细菌病因,并引入靶向治疗。病人出院了。我们认为,在任何非细菌性肺炎病例中,通过PCR肺面板延长诊断可以早期有效地治疗患者。在治疗病毒感染过程中的肺间质病变患者时,应始终牢记非典型合并感染的可能性。
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Bacterial complications in patients with coronavirus infection, new diagnostic and therapeutic possibilities.

We present the case of a young patient who developed pneumonia during the COVID-19 outbreak. The course of the disease with involvement of interstitial lung tissue atypical for bacterial infections, the picture of infection markers could indicate SARS-CoV-2. The patient was tested by PCR method on admission with negative results. Due to the atypical follow-up of the disease, suggesting a severe course of SARS, PCR testing of the material collected by BAL was performed BIOFIRE® FILMARRAY® Pneumonia plus Panel (bioMérieux). Legionella pneumophilla and coronavirus genetic materials were found. We conclude that in the described case there was a bacterial co-infection, paved by virus infection. The similar radiological picture of the two cases of pneumonia, as well as the similar infectious response in the blood, specific for atypical infections, may pose a problem in the differential diagnosis. The study was able to confirm the bacterial etiology of pneumonia and introduce targeted treatment. The patient was discharged from the hospital. We believe that in any case of pneumonia of non-bacterial etiology, extending the diagnosis with a PCR pulmonary panel allows early and effective treatment of patients. In the treatment of patients with pulmonary interstitial lesions in the course of virus infections, one should always keep in mind the possibility of atypical co-infections.

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来源期刊
Przeglad epidemiologiczny
Przeglad epidemiologiczny Medicine-Medicine (all)
CiteScore
1.10
自引率
0.00%
发文量
64
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