弗雷德里克·格兰特·班廷爵士——胰岛素的发现者。在诺贝尔奖100周年之际。

Q3 Medicine Przeglad epidemiologiczny Pub Date : 2023-01-01 DOI:10.32394/pe.77.11
Konrad Barszczewski, Radosław Karaś, Martyna Biadasiewicz, Halina Kulik, Tomasz Lepich
{"title":"弗雷德里克·格兰特·班廷爵士——胰岛素的发现者。在诺贝尔奖100周年之际。","authors":"Konrad Barszczewski,&nbsp;Radosław Karaś,&nbsp;Martyna Biadasiewicz,&nbsp;Halina Kulik,&nbsp;Tomasz Lepich","doi":"10.32394/pe.77.11","DOIUrl":null,"url":null,"abstract":"<p><p>Over the past thousands of years, diabetes has deprived people all over the world of their lives. Until 1922, mankind remained powerless. However, change came, with Frederick Banting (1891-1941), the discoverer of insulin. This breakthrough discovery was made not by a great scientist, but by a hard-working and persistent doctor. Perhaps Banting's conscientiousness and integrity stemmed from where he grew up? A small farm in the provinces certainly influenced his further development. A development that was not obvious, because as a child little Freddie had learning difficulties. Determination led him to medicine. It must not have been without surprise to Professor MacLeod (1876-1935) when, in his office at the University of Ontario, he heard from the 30-year-old doctor that he had an idea on how to save lives from an incurable disease. The opportunity Banting was given, he used effectively. Together with the help of his student Charles Best (1899-1978), he isolated insulin. The dissemination of insulin in Poland was very quickly taken up by Kazimierz Funk (1884-1967), the discoverer of thiamine and creator of the term 'vitamin'. As head of the Department of Biochemistry at the National Institute of Hygiene (PZH), he began producing insulin from bovine pancreases in 1924. He carried out this initiative using his private funds, equipping the laboratory with the appropriate equipment. Banting's remarkable feat was rewarded in 1923. Nobel Prize, which he shared with MacLeod. The fact that the actual co-discoverer of insulin, Charles Best, was not included in the award outraged Banting to such an extent that he decided not to accept the prize. After much persuasion, he changed his mind, but shared the financial reward with his faithful assistant. The discoverer's determination and behaviour in the face of success provides an invaluable lesson for today's doctors and scientists. By following the principles Banting espoused, we can honour his memory.</p>","PeriodicalId":20777,"journal":{"name":"Przeglad epidemiologiczny","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"1","resultStr":"{\"title\":\"Sir Frederick Grant Banting - the discoverer of insulin. On the 100th anniversary on the Nobel Prize.\",\"authors\":\"Konrad Barszczewski,&nbsp;Radosław Karaś,&nbsp;Martyna Biadasiewicz,&nbsp;Halina Kulik,&nbsp;Tomasz Lepich\",\"doi\":\"10.32394/pe.77.11\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Over the past thousands of years, diabetes has deprived people all over the world of their lives. Until 1922, mankind remained powerless. However, change came, with Frederick Banting (1891-1941), the discoverer of insulin. This breakthrough discovery was made not by a great scientist, but by a hard-working and persistent doctor. Perhaps Banting's conscientiousness and integrity stemmed from where he grew up? A small farm in the provinces certainly influenced his further development. A development that was not obvious, because as a child little Freddie had learning difficulties. Determination led him to medicine. It must not have been without surprise to Professor MacLeod (1876-1935) when, in his office at the University of Ontario, he heard from the 30-year-old doctor that he had an idea on how to save lives from an incurable disease. The opportunity Banting was given, he used effectively. Together with the help of his student Charles Best (1899-1978), he isolated insulin. The dissemination of insulin in Poland was very quickly taken up by Kazimierz Funk (1884-1967), the discoverer of thiamine and creator of the term 'vitamin'. As head of the Department of Biochemistry at the National Institute of Hygiene (PZH), he began producing insulin from bovine pancreases in 1924. He carried out this initiative using his private funds, equipping the laboratory with the appropriate equipment. Banting's remarkable feat was rewarded in 1923. Nobel Prize, which he shared with MacLeod. The fact that the actual co-discoverer of insulin, Charles Best, was not included in the award outraged Banting to such an extent that he decided not to accept the prize. After much persuasion, he changed his mind, but shared the financial reward with his faithful assistant. The discoverer's determination and behaviour in the face of success provides an invaluable lesson for today's doctors and scientists. By following the principles Banting espoused, we can honour his memory.</p>\",\"PeriodicalId\":20777,\"journal\":{\"name\":\"Przeglad epidemiologiczny\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Przeglad epidemiologiczny\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.32394/pe.77.11\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Przeglad epidemiologiczny","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.32394/pe.77.11","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 1

摘要

在过去的几千年里,糖尿病夺走了全世界人民的生命。直到1922年,人类仍然无能为力。然而,胰岛素的发现者弗雷德里克·班廷(Frederick Banting, 1891-1941)带来了改变。这一突破性的发现不是由一位伟大的科学家,而是由一位勤奋而坚持不懈的医生做出的。也许班廷的认真和正直源于他成长的地方?外省的一个小农场无疑影响了他的进一步发展。这一发展并不明显,因为小弗莱迪小时候有学习困难。决心使他从医。当麦克劳德教授(1876-1935)在安大略大学的办公室里听到这位30岁的医生说,他有一个从不治之症中拯救生命的想法时,他一定很惊讶。班廷有效地利用了这个机会。在他的学生查尔斯·贝斯特(1899-1978)的帮助下,他分离出胰岛素。胰岛素在波兰的推广很快就被硫胺素的发现者和“维生素”一词的发明者Kazimierz Funk(1884-1967)所接受。作为国家卫生研究所生物化学系的主任,他于1924年开始用牛的胰腺生产胰岛素。他利用自己的私人资金实施了这项倡议,为实验室配备了适当的设备。班廷的非凡成就在1923年得到了奖励。他和麦克劳德分享了诺贝尔奖。胰岛素的真正共同发现者查尔斯·贝斯特(Charles Best)没有被列入该奖项,这一事实激怒了班廷,他决定不接受该奖项。经过多次劝说,他改变了主意,但把奖金分给了他忠实的助手。这位发现者面对成功的决心和行为为今天的医生和科学家提供了宝贵的经验。通过遵循班廷所倡导的原则,我们可以纪念他。
本文章由计算机程序翻译,如有差异,请以英文原文为准。
查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Sir Frederick Grant Banting - the discoverer of insulin. On the 100th anniversary on the Nobel Prize.

Over the past thousands of years, diabetes has deprived people all over the world of their lives. Until 1922, mankind remained powerless. However, change came, with Frederick Banting (1891-1941), the discoverer of insulin. This breakthrough discovery was made not by a great scientist, but by a hard-working and persistent doctor. Perhaps Banting's conscientiousness and integrity stemmed from where he grew up? A small farm in the provinces certainly influenced his further development. A development that was not obvious, because as a child little Freddie had learning difficulties. Determination led him to medicine. It must not have been without surprise to Professor MacLeod (1876-1935) when, in his office at the University of Ontario, he heard from the 30-year-old doctor that he had an idea on how to save lives from an incurable disease. The opportunity Banting was given, he used effectively. Together with the help of his student Charles Best (1899-1978), he isolated insulin. The dissemination of insulin in Poland was very quickly taken up by Kazimierz Funk (1884-1967), the discoverer of thiamine and creator of the term 'vitamin'. As head of the Department of Biochemistry at the National Institute of Hygiene (PZH), he began producing insulin from bovine pancreases in 1924. He carried out this initiative using his private funds, equipping the laboratory with the appropriate equipment. Banting's remarkable feat was rewarded in 1923. Nobel Prize, which he shared with MacLeod. The fact that the actual co-discoverer of insulin, Charles Best, was not included in the award outraged Banting to such an extent that he decided not to accept the prize. After much persuasion, he changed his mind, but shared the financial reward with his faithful assistant. The discoverer's determination and behaviour in the face of success provides an invaluable lesson for today's doctors and scientists. By following the principles Banting espoused, we can honour his memory.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Przeglad epidemiologiczny
Przeglad epidemiologiczny Medicine-Medicine (all)
CiteScore
1.10
自引率
0.00%
发文量
64
期刊最新文献
A 13- year- old patient with acute cerebral nocardiosis: Case report and review. A retrospective study to evaluate the safety and efficacy of intrapleural alteplase in pediatric empyema. Blood infection of Capnocytophaga canimorsus etiology following a dog bite: case report and review of the available literature. Diagnosis of an atypical fever in a 55-year-old man. Hepatitis C in Poland in 2022.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1