【皮肤药物不良反应的鉴别】。

Q4 Medicine Revue Du Praticien Pub Date : 2023-03-01
Saskia Ingen-Housz-Oro
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引用次数: 0

摘要

皮肤药物不良反应的鉴别。皮肤药物不良反应是常见的。最常见的是黄斑丘疹,几天内就会愈合。然而,临床和生物学的严重迹象应排除。严重的药物反应包括急性全身性脓疱病、DRESS(伴有嗜酸性粒细胞增多和全身性症状的药物反应)和表皮坏死松解(Stevens-Johnson和Lyell综合征)。对可疑药物的搜索是基于对患者或其随行人员的询问和时间顺序。药疹的治疗取决于其疾病类型和患者的背景。对于任何严重的药物反应,住院治疗是必要的。由于致残后遗症的频繁,表皮坏死松解的随访时间应延长。所有药物反应,特别是严重的药物反应,都必须向药物警戒部门申报。
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[Identification of cutaneous adverse drug reactions].

IDENTIFICATION OF CUTANEOUS ADVERSE DRUG REACTIONS. Cutaneous adverse drug reactions are common. The most common are maculopapular exanthemas, which heal within a few days. However, clinical and biological signs of severity should be ruled out. Severe drug reactions include acute generalized exanthematous pustulosis, DRESS (drug reaction with eosinophilia and systemic symptoms), and epidermal necrolysis (Stevens-Johnson and Lyell syndromes). The search for the suspect drug is based on the questioning of the patient or his entourage and a chronological timeline. The treatment of drug eruption depends on its nosological type and the patient's background. For any severe drug reaction, hospitalization in a specialized units is necessary. Follow-up of epidermal necrolysis should be prolonged due to the frequency of disabling sequelae. All drug reactions, in particular the severe forms, must be declared to the pharmacovigilance services.

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来源期刊
Revue Du Praticien
Revue Du Praticien Medicine-Medicine (all)
CiteScore
0.20
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0.00%
发文量
161
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