中高危急性肺栓塞患者的真实世界特征和预后。

Q3 Medicine Acute Medicine Pub Date : 2023-01-01 DOI:10.52964/AMJA.0936

Ajc Overgaauw, L J Meijboom, J van Es, E J Lust, E H Serne, Pwb Nanayakkara, Y M Smulders, A J Kooter, R W Sprengers, H J de Grooth, R J Lely, A Thijs, A Vonk Noordegraaf, Lma Heunks, Pwg Elbers, H J Bogaard, P R Tuinman, E J Nossent

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引用次数: 0

摘要

背景:目前推荐的密切监测中高危急性肺栓塞(PE)患者的确切益处尚不清楚。方法:该前瞻性观察队列研究确定了一家学术医院中中度高风险急性PE患者的临床特征和病程。血流动力学恶化的频率、抢救性再灌注治疗的使用和PE相关的死亡率是我们感兴趣的结果。结果:98例中高危PE患者纳入分析，81例(83%)患者受到密切监测。2例血流动力学恶化，经抢救性再灌注治疗。在此之后，一名患者存活了下来。结论:98例中高危PE患者中，3例发生血流动力学恶化，2例经严密监测的抢救性再灌注治疗，1例存活。强调需要更好地认识和研究患者受益于密切监测的最佳方式。

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Real-world characteristics and outcomes of patients with intermediate high risk acute pulmonary embolism.

Background: Exact benefits of currently recommended close monitoring in intermediate high risk acute pulmonary embolism (PE) patients are unknown.

Methods: This prospective observational cohort study determined clinical characteristics, and disease course of intermediate high risk acute PE patients in an academic hospital setting . Frequency of hemodynamic deterioration, use of rescue reperfusion therapy and PE related mortality, were outcomes of interest.

Results: Of 98 intermediate high risk PE patients included for analysis, 81 patients (83%) were closely monitored. Two deteriorated hemodynamically and were treated with rescue reperfusion therapy. One patient survived after this.

Conclusions: In these 98 intermediate high risk PE patients, hemodynamic deterioration occurred in three patients and rescue reperfusion therapy of two closely monitored patients led to survival of one. Underlining the need for better recognition of patients benefitting from and research in the optimal way of close monitoring.

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来源期刊

Acute Medicine Medicine-Emergency Medicine

CiteScore

1.50

自引率

0.00%

发文量

期刊介绍： These are usually commissioned by the editorial team in accordance with a cycle running over several years. Authors wishing to submit a review relevant to Acute Medicine are advised to contact the editor before writing this. Unsolicited review articles received for consideration may be included if the subject matter is considered of interest to the readership, provided the topic has not already been covered in a recent edition. Review articles are usually 3000-5000 words and may include tables, pictures and other figures as required for the text. Include 3 or 4 ‘key points’ summarising the main teaching messages.