淋巴细胞减少症预示着犬肝细胞癌生存率的降低。

IF 1.5 3区农林科学 Q2 VETERINARY SCIENCES Journal of Veterinary Science Pub Date : 2023-05-01 DOI:10.4142/jvs.22266

Jose Israel Suarez-Rodriguez, Chin-Chi Liu, Shannon Dehghanpir, Andrea N Johnston

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引用次数: 0

摘要

血小板与淋巴细胞比值（PLR）是人类肝细胞癌（HCC）的预后标志物，但其在犬类 HCC 中的应用尚未得到探讨。本研究旨在确定 PLR 是否能预测 42 只患 HCC 的狗的生存结果。PLR不是一个重要的预测因素（p = 0.15），但淋巴细胞减少症本身与生存概率降低显著相关（p = 0.024）。还需要进一步的研究来评估外周淋巴细胞计数是否反映了犬 HCC 肿瘤微环境的情况。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Lymphopenia predicts reduced survival in canine hepatocellular carcinoma.

Platelet to lymphocyte ratio (PLR) is a prognostic marker in human hepatocellular carcinoma (HCC) however, its utility in canine HCC has not been explored. The aim of the study was to determine if PLR could predict survival outcomes in 42 dogs with HCC. PLR was not a significant predictive factor (p = 0.15) but lymphopenia alone was significantly correlated with a reduced probability of survival (p = 0.024). Further studies are needed to evaluate if peripheral lymphocyte count mirrors that of the tumor microenvironment in canine HCC.

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来源期刊

Journal of Veterinary Science 农林科学-兽医学

CiteScore

3.10

自引率

5.60%

发文量

审稿时长

1.3 months

期刊介绍： The Journal of Veterinary Science (J Vet Sci) is devoted to the advancement and dissemination of scientific knowledge concerning veterinary sciences and related academic disciplines. It is an international journal indexed in the Thomson Scientific Web of Science, SCI-EXPANDED, Sci Search, BIOSIS Previews, Biological Abstracts, Focus on: Veterinary Science & Medicine, Zoological Record, PubMed /MEDLINE, Index Medicus, Pubmed Central, CAB Abstracts / Index Veterinarius, EBSCO, AGRIS and AGRICOLA. This journal published in English by the Korean Society of Veterinary Science (KSVS) being distributed worldwide.