胰腺癌临床试验中的种族差异:界定问题并找出解决方案。

2区 医学 Q1 Medicine Advances in Cancer Research Pub Date : 2023-01-01 Epub Date: 2023-03-13 DOI:10.1016/bs.acr.2023.02.009
Allison N Martin, Rebecca A Snyder
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引用次数: 1

摘要

代表性不足的少数族裔胰腺癌患者在接受癌症治疗(包括临床试验)方面存在差异。成功开展并完成临床试验对于改善胰腺癌患者的治疗效果至关重要。因此,必须考虑如何最大限度地提高患者参与治疗性和非治疗性临床试验的资格。对于临床医生和医疗系统来说,了解个人、临床医生和系统层面在招募、注册和完成临床试验方面存在的障碍以减少偏见非常重要。了解能提高代表性不足的少数群体、社会经济条件较差的个人和服务不足的社区的入选率的策略,将提高癌症临床试验的普及性并促进健康公平。
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Racial disparities in pancreatic cancer clinical trials: Defining the problem and identifying solutions.

Underrepresented minority patients with pancreatic cancer have differential access to cancer treatments, including clinical trials. The successful conduct and completion of clinical trials is critical to improve outcomes for patients with pancreatic cancer. Therefore, it is essential to consider how to maximize eligibility of patients for both therapeutic and non-therapeutic clinical trials. It is important for clinicians and for the health system to understand individual-, clinician-, and system-level barriers to recruitment, enrollment, and completion of clinical trials to alleviate bias. Understanding strategies that lead to improved enrollment of underrepresented minorities, socioeconomically disadvantaged individuals, and underserved communities will improve generalizability of cancer clinical trials and advance health equity.

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来源期刊
Advances in Cancer Research
Advances in Cancer Research 医学-肿瘤学
CiteScore
10.00
自引率
0.00%
发文量
52
期刊介绍: Advances in Cancer Research (ACR) has covered a remarkable period of discovery that encompasses the beginning of the revolution in biology. Advances in Cancer Research (ACR) has covered a remarkable period of discovery that encompasses the beginning of the revolution in biology. The first ACR volume came out in the year that Watson and Crick reported on the central dogma of biology, the DNA double helix. In the first 100 volumes are found many contributions by some of those who helped shape the revolution and who made many of the remarkable discoveries in cancer research that have developed from it.
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