不披露HIV阳性血清状态:埃塞俄比亚南部Gedeo区公共卫生机构中HIV感染者的非匹配病例对照研究

IF 1.5 Q4 INFECTIOUS DISEASES HIV AIDS-Research and Palliative Care Pub Date : 2023-01-01 DOI:10.2147/HIV.S405818
Betelhem Tadesse Tessema, Girma Tenkolu Bune, Zerihun Berhanu Mamo
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引用次数: 3

摘要

背景:不披露艾滋病毒阳性状态(NDHPSS)是指个人对他人或群体隐瞒其艾滋病毒感染状况的经历。未能透露其艾滋病毒阳性血清状态的人有再次感染病毒的风险,无法得到最好的治疗,甚至死亡。目的:评估埃塞俄比亚南部gedeo区公共卫生机构中艾滋病毒感染者NDHPSS的预测因素。方法:于2022年2月1日至3月30日在埃塞俄比亚南部的Gedeo-Zone开展了一项以设施为基础的、不匹配的病例对照研究。病例与对照比为1:1,共360名应答者(病例89例,对照271例)。使用顺序抽样技术选择受访者。数据录入采用EpiData-V-3.1,分析采用SPSS-V-25。为了确定与结果相关的因素,进行了二元逻辑回归分析。采用95%置信区间的AOR和0.05以下的p值来解释其统计学意义。结果:该研究共有360名参与者,其中对照组271人,病例89人,有效率为97.6%。参与者的平均年龄为35.6岁(SD: 8.3)。调整可能的混杂因素后,性别(AOR = 2.8, 95% CI: 1.04-7.56)、居住地(AOR = 3.52, 95% CI: 2.83-9.39)、WHO临床I期(AOR = 4.68, 95% CI: 1.9-22.1)、抗逆转录病毒治疗随访时间短(AOR = 4.21, 95% CI: 1.65-10.73)和终生性伴侣数量(AOR = 6.9, 95% CI: 1.86-26.3)是与结果显著相关的因素。结论:根据这项研究,生活在农村地区和处于世卫组织临床第一阶段,以及女性和一生中有多个性伴侣,是不披露艾滋病毒阳性血清状态的预测因素。因此,鼓励处于世卫组织第一阶段的艾滋病毒感染者和一生中有一个以上性伴侣的人披露其状况,并扩大对农村居民和妇女的咨询服务,对减少艾滋病毒载量具有重大影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Non-Disclosure of HIV-Positive Serostatus: Unmatched Case-Control Study in People Living with HIV in Public Health Facilities of Gedeo Zone, Southern Ethiopia.

Background: Non-disclosure of HIV-positive status (NDHPSS) is the individual's experience of hiding their HIV status from other people or groups. People who fail to reveal their HIV-positive serostatus risk contracting the virus again, not receiving the best possible care, and even dying.

Purpose: To assess predictors of NDHPSS in people living with HIV in public health facilities in Gedeo-Zone, Southern-Ethiopia.

Methods: In Gedeo-Zone, Southern Ethiopia, a facility-based, unmatched, case-control study was carried out from the first of February to March 30, 2022GC. With a case-to-control ratio of 1:1, a total of 360 respondents (89 cases and 271 controls) were involved. The respondents were chosen using a sequential sampling technique. EpiData-V-3.1 was used to enter the data, and SPSS-V-25 was used to analyse it. To determine the factors that were connected to the result, a binary logistic regression analysis was performed. AOR at the 95% confidence interval and p-values under 0.05 were utilised to explain their statistical significance.

Results: The study had 360 participants in total-271 controls and 89 cases-resulting in a response rate of 97.6%. The average age of the participants was 35.6 years (SD: 8.3). After adjusting the possible confounders, sex (AOR = 2.8, 95% CI: 1.04-7.56), residence (AORs = 3.52, 95% CI: 2.83-9.39), WHO clinical stage I (AORs = 4.68, 95% CI: 1.9-22.1), short duration of ART follow-up care (AOR = 4.21, 95% CI: 1.65-10.73), and number of lifetime sexual partners (AOR = 6.9, 95% CI: 1.86-26.3) were significantly associated factors with the outcome.

Conclusion: According to this study, living in a rural area and being in WHO clinical stage one, in addition to being a woman and having multiple sexual partners during one's lifetime, were predictors of non-disclosure of an HIV-positive serostatus. As a result, encouraging people with HIV in WHO stage I and those who have had more than one sexual partner in their lifetime to disclose their status and expanding counselling services for rural residents and women have a substantial impact on reducing the HIV load.

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CiteScore
3.00
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期刊介绍: About Dove Medical Press Dove Medical Press Ltd is part of Taylor & Francis Group, the Academic Publishing Division of Informa PLC. We specialize in the publication of Open Access peer-reviewed journals across the broad spectrum of science, technology and especially medicine. Dove Medical Press was founded in 2003 with the objective of combining the highest editorial standards with the ''best of breed'' new publishing technologies. We have offices in Manchester and London in the United Kingdom, representatives in Princeton, New Jersey in the United States, and our editorial offices are in Auckland, New Zealand. Dr Scott Fraser is our Medical Director based in the UK. He has been in full time clinical practice for over 20 years as well as having an active research interest.
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