鼻内细菌、病毒和免疫系统的相互作用。

Matthew Flynn, Zinnia Lyall, Gwendolyn Shepherd, Osher Ngo Yung Lee, Ioannou Marianna Da Fonseca, Yijia Dong, Stuart Chalmers, Jamie Hare, Jack Thomson, Freya Millar
{"title":"鼻内细菌、病毒和免疫系统的相互作用。","authors":"Matthew Flynn,&nbsp;Zinnia Lyall,&nbsp;Gwendolyn Shepherd,&nbsp;Osher Ngo Yung Lee,&nbsp;Ioannou Marianna Da Fonseca,&nbsp;Yijia Dong,&nbsp;Stuart Chalmers,&nbsp;Jamie Hare,&nbsp;Jack Thomson,&nbsp;Freya Millar","doi":"10.1093/femsmc/xtac020","DOIUrl":null,"url":null,"abstract":"<p><p>Emerging evidence suggests that the nasal microbiome may influence host susceptibility to initial development and severity of respiratory viral infections. While not as extensively studied as the microbiota of the alimentary tract, it is now clearly established that the microbial composition of this niche is influenced by medical, social and pharmacological influences, predisposing some sub-populations to respiratory infections. The resulting specific microbial profiles may explain variance in susceptibility to viral infection. This review summaries the evolution and constituents of the commensal nasal microbiome; the bacterial-virus, bacterial-host and interbacterial interactions which potentiate disease; and considers the effects of interventions such as vaccination and probiotics.</p>","PeriodicalId":73024,"journal":{"name":"FEMS microbes","volume":"3 ","pages":"xtac020"},"PeriodicalIF":0.0000,"publicationDate":"2022-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/52/12/xtac020.PMC10117739.pdf","citationCount":"1","resultStr":"{\"title\":\"Interactions of the bacteriome, virome, and immune system in the nose.\",\"authors\":\"Matthew Flynn,&nbsp;Zinnia Lyall,&nbsp;Gwendolyn Shepherd,&nbsp;Osher Ngo Yung Lee,&nbsp;Ioannou Marianna Da Fonseca,&nbsp;Yijia Dong,&nbsp;Stuart Chalmers,&nbsp;Jamie Hare,&nbsp;Jack Thomson,&nbsp;Freya Millar\",\"doi\":\"10.1093/femsmc/xtac020\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><p>Emerging evidence suggests that the nasal microbiome may influence host susceptibility to initial development and severity of respiratory viral infections. While not as extensively studied as the microbiota of the alimentary tract, it is now clearly established that the microbial composition of this niche is influenced by medical, social and pharmacological influences, predisposing some sub-populations to respiratory infections. The resulting specific microbial profiles may explain variance in susceptibility to viral infection. This review summaries the evolution and constituents of the commensal nasal microbiome; the bacterial-virus, bacterial-host and interbacterial interactions which potentiate disease; and considers the effects of interventions such as vaccination and probiotics.</p>\",\"PeriodicalId\":73024,\"journal\":{\"name\":\"FEMS microbes\",\"volume\":\"3 \",\"pages\":\"xtac020\"},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2022-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/52/12/xtac020.PMC10117739.pdf\",\"citationCount\":\"1\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"FEMS microbes\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1093/femsmc/xtac020\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"\",\"JCRName\":\"\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"FEMS microbes","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1093/femsmc/xtac020","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"","JCRName":"","Score":null,"Total":0}
引用次数: 1

摘要

新出现的证据表明,鼻腔微生物组可能影响宿主对呼吸道病毒感染的初始发展和严重程度的易感性。虽然没有像消化道的微生物群那样得到广泛的研究,但现在已经清楚地确定,这一生态位的微生物组成受到医疗、社会和药理学影响,使一些亚群易患呼吸道感染。由此产生的特定微生物谱可以解释对病毒感染易感性的差异。本文综述了共生鼻腔微生物群的进化和组成;引起疾病的细菌-病毒、细菌-宿主和细菌间的相互作用;并考虑了疫苗接种和益生菌等干预措施的影响。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

摘要图片

摘要图片

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Interactions of the bacteriome, virome, and immune system in the nose.

Emerging evidence suggests that the nasal microbiome may influence host susceptibility to initial development and severity of respiratory viral infections. While not as extensively studied as the microbiota of the alimentary tract, it is now clearly established that the microbial composition of this niche is influenced by medical, social and pharmacological influences, predisposing some sub-populations to respiratory infections. The resulting specific microbial profiles may explain variance in susceptibility to viral infection. This review summaries the evolution and constituents of the commensal nasal microbiome; the bacterial-virus, bacterial-host and interbacterial interactions which potentiate disease; and considers the effects of interventions such as vaccination and probiotics.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
CiteScore
3.30
自引率
0.00%
发文量
0
审稿时长
15 weeks
期刊最新文献
Evaluating the impact of redox potential on the growth capacity of anaerobic gut fungi. Contact with young children is a major risk factor for pneumococcal colonization in older adults. Trivalent immunization with metal-binding proteins confers protection against enterococci in a mouse infection model. Arginine impacts aggregation, biofilm formation, and antibiotic susceptibility in Enterococcus faecalis. Pandemic storytelling and student engagement: how students imagined pandemics before COVID-19 pandemic.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1