动态腹部肥胖会增加年龄≥50 岁的成年人跌倒的风险:爱尔兰老龄化纵向研究前瞻性分析》。

IF 4.3 2区 医学 Q1 GERIATRICS & GERONTOLOGY Journals of Gerontology Series A-Biological Sciences and Medical Sciences Pub Date : 2024-01-01 DOI:10.1093/gerona/glad104
Lee Smith, Guillermo F López Sánchez, Nicola Veronese, Pinar Soysal, Masoud Rahmati, Louis Jacob, Karel Kostev, Josep Maria Haro, Abdullah Ahmed Alghamdi, Laurie Butler, Yvonne Barnett, Helen Keyes, Mark A Tully, Jae Il Shin, Ai Koyanagi
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引用次数: 0

摘要

背景:很少有研究探讨动态腹型肥胖(DAO;即肌肉力量受损和腰围过高)与未来跌倒风险之间的纵向关系。因此,我们以爱尔兰具有全国代表性的中老年人为样本,旨在调查基线DAO与2年随访期间发生的跌倒之间的前瞻性关联:我们对爱尔兰老龄化纵向研究调查连续两波的数据进行了分析。女性握力为 88 厘米,男性握力大于 102 厘米。DAO在第1波(2009-2011年)进行了评估,定义为同时患有动力不足症和腹部肥胖症。第 1 波和第 2 波(2012-2013 年)之间发生的跌倒均为自我报告。进行了多变量逻辑回归分析:分析了 5 275 名年龄≥50 岁者的数据(平均 [标准差 {SD}] 年龄为 63.2 [8.9] 岁;48.8% 为男性)。在对潜在的混杂因素进行调整后,与基线时无动态脂蛋白减少症和无腹部肥胖症相比,DAO 与 2 年随访时跌倒几率增加 1.47 倍(95% 置信区间 [CI]:1.14-1.89)有显著相关性。而单纯的动力性肥胖(几率比 [OR] = 1.08;95% CI:0.84-1.40)和单纯的腹部肥胖(OR = 1.09;95% CI:0.91-1.29)与随访时的跌倒没有明显关系:DAO增加了爱尔兰中老年人跌倒的风险。预防或扭转DAO的干预措施可能有利于减少跌倒。
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Dynapenic Abdominal Obesity Increases Risk for Falls Among Adults Aged ≥50 Years: A Prospective Analysis of the Irish Longitudinal Study on Ageing.

Background: There is a scarcity of studies examining the longitudinal relationship between dynapenic abdominal obesity (DAO; ie, impairment in muscle strength and high waist circumference) and future fall risk. Therefore, we aimed to investigate the prospective association between DAO at baseline and falls occurring during 2 years of follow-up in a nationally representative sample of middle-aged and older individuals from Ireland.

Methods: Data from 2 consecutive waves of the Irish Longitudinal Study on Ageing survey were analyzed. Dynapenia was defined as handgrip strength of <26 kg for men and <16 kg for women. Abdominal obesity was defined as a waist circumference of >88 cm for women and >102 cm for men. DAO was assessed at Wave 1 (2009-2011) and was defined as having both dynapenia and abdominal obesity. Falls occurring between Wave 1 and Wave 2 (2012-2013) were self-reported. Multivariable logistic regression analysis was conducted.

Results: Data on 5 275 individuals aged ≥50 years were analyzed (mean [standard deviation {SD}] age 63.2 [8.9] years; 48.8% males). After adjustment for potential confounders, compared to no dynapenia and no abdominal obesity at baseline, DAO was significantly associated with 1.47 (95% confidence interval [CI]: 1.14-1.89) times higher odds for falls at 2-year follow-up. Dynapenia alone (odds ratio [OR] = 1.08; 95% CI: 0.84-1.40) and abdominal obesity alone (OR = 1.09; 95% CI: 0.91-1.29) were not significantly associated with falls at follow-up.

Conclusions: DAO increased the risk for falls among middle-aged and older adults in Ireland. Interventions to prevent or reverse DAO may be beneficial for fall reduction.

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来源期刊
CiteScore
10.00
自引率
5.90%
发文量
233
审稿时长
3-8 weeks
期刊介绍: Publishes articles representing the full range of medical sciences pertaining to aging. Appropriate areas include, but are not limited to, basic medical science, clinical epidemiology, clinical research, and health services research for professions such as medicine, dentistry, allied health sciences, and nursing. It publishes articles on research pertinent to human biology and disease.
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