产前酒精暴露青少年的听觉结果

IF 2.3 4区 医学 Q2 DEVELOPMENTAL BIOLOGY Developmental Neuroscience Pub Date : 2023-01-01 DOI:10.1159/000528846
Humberto de Oliveira Simões, Eduardo Tanaka Massuda, Erikson Felipe Furtado, Sthella Zanchetta
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引用次数: 1

摘要

本研究的目的是研究胎儿酒精暴露后无表型改变的青少年听觉功能的三个方面(听觉敏锐度、耳蜗功能障碍和听觉加工)。从一项队列研究中选择了51名有或没有宫内酒精暴露的青少年。对结果的传唤、评价和分析是盲目地针对各自的酒精暴露进行的。听觉测试包括纯音测听、瞬态耳声发射和听觉处理行为评估(噪音中的语音、二位数和噪音中的间隙)。测试后,45名青少年被纳入评估,分为暴露组(n = 22)和未暴露组(n = 23)。暴露组中有1名受试者出现听力损失(4.5%)。在没有听力损失的情况下,两组之间的音调阈值和感觉(耳蜗)反应的大小没有显著差异(p > 0.05)。两组在处理测试中的表现也没有差异(语音噪声p = 0.71,二分p = 0.94,噪声间隙p = 0.33)。然而,暴露组比未暴露组有更多的听力障碍(听力损失加听觉处理障碍)(22.7%比4.3%)。
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Auditory Outcomes in Adolescents with Prenatal Alcohol Exposure.

The aim of the study was to investigate three aspects of auditory function (auditory acuity, cochlear dysfunction, and auditory processing) in adolescents with fetal alcohol exposure without phenotypic changes. Fifty-one adolescents with and without intrauterine exposure to alcohol were selected from a cohort study. The summons, evaluation, and analysis of the results were carried out blindly regarding the respective exposure to alcohol. The auditory tests were pure-tone audiometry, transient otoacoustic emissions, and behavioral assessment of auditory processing (speech-in-noise, dichotic digits, and gap-in-noise). After testing, 45 adolescents were included in the evaluation and were divided into exposed (n = 22) and non-exposed (n = 23) groups. Hearing loss was identified in one subject in the exposed group (4.5%). In the absence of hearing loss, there were no significant differences in tonal thresholds or in the magnitudes of the sensory (cochlear) responses between groups (p > 0.05). There was also no difference between the two groups regarding performance on the processing tests (speech-in-noise p = 0.71, dichotic p = 0.94, and gap-in-noise p = 0.33). However, the exposed group had more cases of hearing disorders (hearing loss plus auditory processing disorders) than the non-exposed group (22.7% vs. 4.3%).

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来源期刊
Developmental Neuroscience
Developmental Neuroscience 医学-发育生物学
CiteScore
4.00
自引率
3.40%
发文量
49
审稿时长
>12 weeks
期刊介绍: ''Developmental Neuroscience'' is a multidisciplinary journal publishing papers covering all stages of invertebrate, vertebrate and human brain development. Emphasis is placed on publishing fundamental as well as translational studies that contribute to our understanding of mechanisms of normal development as well as genetic and environmental causes of abnormal brain development. The journal thus provides valuable information for both physicians and biologists. To meet the rapidly expanding information needs of its readers, the journal combines original papers that report on progress and advances in developmental neuroscience with concise mini-reviews that provide a timely overview of key topics, new insights and ongoing controversies. The editorial standards of ''Developmental Neuroscience'' are high. We are committed to publishing only high quality, complete papers that make significant contributions to the field.
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