脑深部电刺激治疗帕金森病:回顾与展望

IF 3.2 4区医学 Q2 ENGINEERING, BIOMEDICAL Biomedical Engineering Letters Pub Date : 2022-08-01 DOI:10.1007/s13534-022-00226-y

Anahita Malvea, Farbod Babaei, Chadwick Boulay, Adam Sachs, Jeongwon Park

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引用次数: 4

摘要

帕金森病(PD)是一种神经退行性疾病，表现为由于大脑深部结构多巴胺输入缺失而导致的运动和非运动能力受损。虽然目前还没有治愈PD的方法，但已经开发了各种药物和手术治疗干预措施来控制PD症状。这篇综述探讨了PD治疗的过去、现在和未来的前景，特别关注深部脑刺激(DBS)、提供DBS的手术方法及其局限性。最后，我们将讨论我们小组在脑图绘制方面为DBS靶向所做的努力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Deep brain stimulation for Parkinson's Disease: A Review and Future Outlook.

Parkinson's Disease (PD) is a neurodegenerative disorder that manifests as an impairment of motor and non-motor abilities due to a loss of dopamine input to deep brain structures. While there is presently no cure for PD, a variety of pharmacological and surgical therapeutic interventions have been developed to manage PD symptoms. This review explores the past, present and future outlooks of PD treatment, with particular attention paid to deep brain stimulation (DBS), the surgical procedure to deliver DBS, and its limitations. Finally, our group's efforts with respect to brain mapping for DBS targeting will be discussed.

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来源期刊

Biomedical Engineering Letters ENGINEERING, BIOMEDICAL-

CiteScore

6.80

自引率

0.00%

发文量

期刊介绍： Biomedical Engineering Letters (BMEL) aims to present the innovative experimental science and technological development in the biomedical field as well as clinical application of new development. The article must contain original biomedical engineering content, defined as development, theoretical analysis, and evaluation/validation of a new technique. BMEL publishes the following types of papers: original articles, review articles, editorials, and letters to the editor. All the papers are reviewed in single-blind fashion.