脑深部电刺激治疗血泪:病例分析及文献回顾。

Pub Date : 2023-01-01 DOI:10.5334/tohm.765

Zihan Masood, Joseph S Domino, Antonia Gragg, Kim Burchiel, Michael Kinsman, Vibhash D Sharma

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摘要

背景:偏瘫(HC)及其严重形式的偏瘫(HB)是罕见的运动障碍，医学上难以治疗，可能需要手术干预。病例报告:我们报告了3例HC-HB患者，他们通过单侧深部脑刺激(DBS)内苍白球(GPi)获得了有意义的临床改善。我们确定了8例先前用GPi-DBS治疗的HC-HB病例，其中大多数患者的症状得到了显着改善。讨论:GPi-DBS可以在精心挑选的难治性HC-HB患者中考虑。然而，数据仅限于小病例系列，需要进一步研究。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Deep Brain Stimulation for the Treatment of Hemichorea: Case Series and Literature Review.

Background: Hemichorea (HC) and its severe form hemiballismus (HB) are rare movement disorders which can be medically refractory to treatments and may need surgical intervention.

Case report: We report 3 patients with HC-HB who had meaningful clinical improvement with unilateral deep brain stimulation (DBS) of the globus pallidus interna (GPi). We identified 8 prior cases of HC-HB treated with GPi-DBS, and a majority of these patients experienced significant improvement in their symptoms.

Discussion: GPi-DBS can be considered in medically refractory HC-HB in carefully selected patients. However, data is limited to small case series and further studies are needed.

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