2型糖尿病是一种行为障碍吗?通过改变生活方式预防和缓解2型糖尿病的证据综述

Matthias Li, Mohammad Sadiq Jeeyavudeen, Ganesan Arunagirinathan, Joseph Pappachan
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摘要

由于越来越多的久坐不动的生活方式和不健康的饮食习惯,2型糖尿病(T2DM)的患病率在全球范围内稳步上升。目前,糖尿病给卫生保健系统造成的负担是前所未有的,而且每天都在增加。一些观察性研究和随机对照试验提供了临床证据,表明采用饮食干预和严格的运动训练方案可以缓解2型糖尿病。值得注意的是,这些研究为T2DM患者缓解或通过各种非药物行为干预预防具有该疾病危险因素的患者提供了充分的证据。在这篇文章中,我们介绍了两个临床病例,他们通过行为改变,特别是通过采用低能量饮食和运动,显示了T2DM/前驱糖尿病的缓解。我们还讨论了T2DM和肥胖研究的最新进展,重点关注营养干预和运动及其对减肥、改善代谢状况、加强血糖控制和糖尿病缓解的益处。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Is Type 2 Diabetes Mellitus a Behavioural Disorder? An Evidence Review for Type 2 Diabetes Mellitus Prevention and Remission through Lifestyle Modification.

The prevalence of type 2 diabetes mellitus (T2DM) is steadily rising worldwide due to an increasingly sedentary lifestyle combined with unhealthy food habits. Currently, the burden of diabetes on healthcare systems is unprecedented and rising daily. Several observational studies and randomized controlled trials provide clinical evidence that T2DM remission is possible by adopting dietary interventions and a strict exercise training protocol. Notably, these studies provide ample evidence for remission in patients with T2DM or for prevention in those with risk factors for the disease through various non-pharmacological behavioural interventions. In this article, we present two clinical cases of individuals who showed remission from T2DM/prediabetes via behavioural changes, especially through the adoption of a low-energy diet and exercise. We also discuss the recent advances in T2DM and obesity research, focusing on nutritional interventions and exercise and their benefits for weight loss, improved metabolic profile, enhanced glycaemic control and remission of diabetes.

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