Bezold脓肿后诊断为x连锁无球蛋白血症1例。

Q3 Medicine Tokai Journal of Experimental and Clinical Medicine Pub Date : 2023-07-20
Hiroaki Iijima, Kyoko Odagiri, Shohei Yamamoto, Tomoaki Murakami, Atsushi Uchiyama, Yoshiyuki Yamada, Toshihide Inagi, Takanobu Teramura, Kenji Okami, Masashi Hamada
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引用次数: 0

摘要

Bezold's脓肿是中耳炎的颅外并发症,其中颈脓肿从乳突通过口瘘形成,近年来是一种罕见的疾病。在这项研究中,我们经历了x连锁无球蛋白血症,这是由于Bezold的脓肿而发现的。病例:一名12岁男童复发性右侧化脓性中耳炎3个月,于当地耳鼻咽喉科门诊行鼓膜造口及口服抗菌药物治疗。病人因症状复发而到诊所就诊。CT显示右侧乳突细胞外侧皮质骨及乳突骨缺损。患者被转介至我院,当日入院并接受紧急手术。术中发现诊断为急性乳突炎和Bezold脓肿,由乳突炎扩散到5尾锁乳突肌引起。经引流并给予ABPC/SBT后,脓肿消失,患者一般情况好转。随后,入院时进行的血型测试表明免疫球蛋白水平低的影响。经过儿科的仔细检查,诊断为x连锁无球蛋白血症。结果,患者接受了定期免疫球蛋白治疗,没有感染,包括贝佐德脓肿。结论:复发性中耳炎和罕见感染应考虑先天性免疫异常。
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X-linked Agammaglobulinemia Diagnosed Following Bezold's Abscess: A Case Report.

Bezold's abscess is an extracranial complication of otitis media, in which a cervical abscess forms from the mastoid process through an ostial fistula, and is a rare condition in recent years. In this study, we experienced a X-linked agammaglobulinemia, which was discovered due to Bezold's abscess. Case: A 12-year-old boy suffering from recurrent right suppurative otitis media for three months was treated with tympanostomy and oral antibacterial therapy at a local otorhinolaryngology clinic. The patient visited the clinic due to a recurrence of symptoms. CT showed bony defects in the cortical bone and mastoid process of the lateral side of the right mastoid cell. The patient was referred to our hospital, admitted the same day and underwent emergency surgery. Intraoperative findings led to the diagnosis of acute mastoiditis and Bezold's abscess c aused b y mastoiditis spreading to the s ternocleidomastoid muscle. After drainage and administration of ABPC/SBT, the abscess disappeared, and the patient's general condition improved. Subsequently, a blood typing test performed on admission suggested the influence of low immunoglobulin levels. A close examination by the pediatric department led to a diagnosis of X-linked agammaglobulinemia. As a result, the patient receives regular immunoglobulin therapy and has been free of infection, including Bezold's abscess. CONCLUSIONS: In the case of recurrent otitis media and rare infections, congenital immune abnormalities should be considered.

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来源期刊
CiteScore
1.10
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32
期刊介绍: The Tokai Journal of Experimental and Clinical Medicine, also referred to as Tokai Journal, is an official quarterly publication of the Tokai Medical Association. Tokai Journal publishes original articles that deal with issues of clinical, experimental, socioeconomic, cultural and/or historical importance to medical science and related fields. Manuscripts may be submitted as full-length Original Articles or Brief Communications. Tokai Journal also publishes reviews and symposium proceedings. Articles accepted for publication in Tokai Journal cannot be reproduced elsewhere without written permission from the Tokai Medical Association. In addition, Tokai Journal will not be held responsible for the opinions of the authors expressed in the published articles.
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