轮廓双环双散射体系统在质子治疗中产生平束的性能精度研究。

Ahmad Esmaili Torshabi, Rouhollah Ghasemkhani
{"title":"轮廓双环双散射体系统在质子治疗中产生平束的性能精度研究。","authors":"Ahmad Esmaili Torshabi,&nbsp;Rouhollah Ghasemkhani","doi":"10.31661/jbpe.v0i0.2002-1066","DOIUrl":null,"url":null,"abstract":"<p><strong>Background: </strong>At proton radiotherapy, the extracted beam from accelerator is not initially suitable for tumor treatment and a modification is needed for beam shape and energy due to tumor dimension and site. One clinical strategy is the use of double scattering systems known as passive dose delivery technique to generate proper flattening, transversely.</p><p><strong>Objective: </strong>This work aims to design and simulate a new version of double scattering system and compare its performance with another available scatterer system, quantitatively.</p><p><strong>Material and methods: </strong>In this analytical study, Monte Carlo FLUKA code is utilized to simulate the performance of proposed system in generating lateral flat beam. The simulation process is very close to real experimental condition, performed at proton beam irradiation room at Tohoku University in Japan. Moreover, the presence of secondary neutrons, produced due to protons collision with proposed scattering system, is considered as main issue.</p><p><strong>Results: </strong>Final results represent that the proposed scattering system is robust to generate 40 mm flat region with an acceptable uniformity degree. Energy loss caused by current dual scatterer is more than simple ring technique, while the secondary neutrons produced by proposed system are larger than other system.</p><p><strong>Conclusion: </strong>This study simulates the performance of a new dual ring double scattering system. Final results show that there is a close correlation between proposed system and current scattering system. The only concern is about the presence of secondary neutrons mainly at high energy proton particles.</p>","PeriodicalId":38035,"journal":{"name":"Journal of Biomedical Physics and Engineering","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-04-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/60/48/JBPE-13-107.PMC10111111.pdf","citationCount":"0","resultStr":"{\"title\":\"Investigation the Performance Accuracy of Contoured Dual Ring Double Scatterer System for Flat Beam Generation at Proton Therapy.\",\"authors\":\"Ahmad Esmaili Torshabi,&nbsp;Rouhollah Ghasemkhani\",\"doi\":\"10.31661/jbpe.v0i0.2002-1066\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Background: </strong>At proton radiotherapy, the extracted beam from accelerator is not initially suitable for tumor treatment and a modification is needed for beam shape and energy due to tumor dimension and site. One clinical strategy is the use of double scattering systems known as passive dose delivery technique to generate proper flattening, transversely.</p><p><strong>Objective: </strong>This work aims to design and simulate a new version of double scattering system and compare its performance with another available scatterer system, quantitatively.</p><p><strong>Material and methods: </strong>In this analytical study, Monte Carlo FLUKA code is utilized to simulate the performance of proposed system in generating lateral flat beam. The simulation process is very close to real experimental condition, performed at proton beam irradiation room at Tohoku University in Japan. Moreover, the presence of secondary neutrons, produced due to protons collision with proposed scattering system, is considered as main issue.</p><p><strong>Results: </strong>Final results represent that the proposed scattering system is robust to generate 40 mm flat region with an acceptable uniformity degree. Energy loss caused by current dual scatterer is more than simple ring technique, while the secondary neutrons produced by proposed system are larger than other system.</p><p><strong>Conclusion: </strong>This study simulates the performance of a new dual ring double scattering system. Final results show that there is a close correlation between proposed system and current scattering system. The only concern is about the presence of secondary neutrons mainly at high energy proton particles.</p>\",\"PeriodicalId\":38035,\"journal\":{\"name\":\"Journal of Biomedical Physics and Engineering\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-04-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"https://ftp.ncbi.nlm.nih.gov/pub/pmc/oa_pdf/60/48/JBPE-13-107.PMC10111111.pdf\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Journal of Biomedical Physics and Engineering\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.31661/jbpe.v0i0.2002-1066\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Journal of Biomedical Physics and Engineering","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.31661/jbpe.v0i0.2002-1066","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0

摘要

背景:在质子放射治疗中,从加速器中提取的光束最初并不适合肿瘤的治疗,由于肿瘤的尺寸和部位,需要对光束的形状和能量进行修改。一种临床策略是使用双重散射系统,即被动给药技术,以产生适当的横向平坦。目的:设计并模拟一种新型双散射系统,并与另一种现有的散射系统进行定量比较。材料和方法:在本分析研究中,利用蒙特卡罗FLUKA代码模拟了所提出的系统产生横向平梁的性能。在日本东北大学质子束辐照室进行的模拟过程非常接近真实的实验条件。此外,由于质子与所提出的散射系统碰撞而产生的次级中子的存在被认为是主要问题。结果:最终结果表明,所提出的散射系统具有较强的鲁棒性,能够产生均匀度可接受的40 mm平面区域。电流双散射体造成的能量损失大于简单的环形技术,而该系统产生的二次中子比其他系统大。结论:本研究模拟了一种新型双环双散射系统的性能。最后的结果表明,所提出的系统与电流散射系统有密切的相关性。唯一值得关注的是次要中子的存在,主要存在于高能质子粒子中。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

摘要图片

摘要图片

摘要图片

查看原文
分享 分享
微信好友 朋友圈 QQ好友 复制链接
本刊更多论文
Investigation the Performance Accuracy of Contoured Dual Ring Double Scatterer System for Flat Beam Generation at Proton Therapy.

Background: At proton radiotherapy, the extracted beam from accelerator is not initially suitable for tumor treatment and a modification is needed for beam shape and energy due to tumor dimension and site. One clinical strategy is the use of double scattering systems known as passive dose delivery technique to generate proper flattening, transversely.

Objective: This work aims to design and simulate a new version of double scattering system and compare its performance with another available scatterer system, quantitatively.

Material and methods: In this analytical study, Monte Carlo FLUKA code is utilized to simulate the performance of proposed system in generating lateral flat beam. The simulation process is very close to real experimental condition, performed at proton beam irradiation room at Tohoku University in Japan. Moreover, the presence of secondary neutrons, produced due to protons collision with proposed scattering system, is considered as main issue.

Results: Final results represent that the proposed scattering system is robust to generate 40 mm flat region with an acceptable uniformity degree. Energy loss caused by current dual scatterer is more than simple ring technique, while the secondary neutrons produced by proposed system are larger than other system.

Conclusion: This study simulates the performance of a new dual ring double scattering system. Final results show that there is a close correlation between proposed system and current scattering system. The only concern is about the presence of secondary neutrons mainly at high energy proton particles.

求助全文
通过发布文献求助,成功后即可免费获取论文全文。 去求助
来源期刊
Journal of Biomedical Physics and Engineering
Journal of Biomedical Physics and Engineering Medicine-Radiology, Nuclear Medicine and Imaging
CiteScore
2.90
自引率
0.00%
发文量
64
审稿时长
10 weeks
期刊介绍: The Journal of Biomedical Physics and Engineering (JBPE) is a bimonthly peer-reviewed English-language journal that publishes high-quality basic sciences and clinical research (experimental or theoretical) broadly concerned with the relationship of physics to medicine and engineering.
期刊最新文献
A Neural Network-based Approach to Prediction of Preterm Birth using Non-invasive Tests. Altered Amplitude of Low-Frequency Fluctuations of rs-fMRI Signal followed by rTMS Analgesic Effects in Non-Specific Chronic Low Back Pain (CLBP) Patients. Comparative Evaluation of LED Light Application and Heat Generation with Three Different Wavelengths of Frequency on Soft Tissues in Bringing Faster Orthodontic Tooth Movement: A Finite Element Model Study. Feasibility of Robot-Assistance Hand Physiotherapy in Post-Stroke Patients. Impact of Electronic Collimation on Reducing Unnecessary Patient Dose in Digital Radiography.
×
引用
GB/T 7714-2015
复制
MLA
复制
APA
复制
导出至
BibTeX EndNote RefMan NoteFirst NoteExpress
×
×
提示
您的信息不完整,为了账户安全,请先补充。
现在去补充
×
提示
您因"违规操作"
具体请查看互助需知
我知道了
×
提示
现在去查看 取消
×
提示
确定
0
微信
客服QQ
Book学术公众号 扫码关注我们
反馈
×
意见反馈
请填写您的意见或建议
请填写您的手机或邮箱
已复制链接
已复制链接
快去分享给好友吧!
我知道了
×
扫码分享
扫码分享
Book学术官方微信
Book学术文献互助
Book学术文献互助群
群 号:481959085
Book学术
文献互助 智能选刊 最新文献 互助须知 联系我们:info@booksci.cn
Book学术提供免费学术资源搜索服务,方便国内外学者检索中英文文献。致力于提供最便捷和优质的服务体验。
Copyright © 2023 Book学术 All rights reserved.
ghs 京公网安备 11010802042870号 京ICP备2023020795号-1