尼日利亚西南部一家三级医疗机构预防母婴传播计划的评估。

IF 1.3 4区 医学 Q4 INFECTIOUS DISEASES Japanese journal of infectious diseases Pub Date : 2023-09-22 Epub Date: 2023-06-30 DOI:10.7883/yoken.JJID.2022.606
Abiodun Folashade Adekanmbi, Samuel Olufemi Akodu, Tinuade Adetutu Ogunlesi, Olusoga Babatunde Ogunfowora, Olusoji Edward Jagun, Victor Ayodeji Ayeni, Omotola Toyin Ojo, Daniel Damilare Ogbaro
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引用次数: 0

摘要

大多数儿童通过母婴传播感染了人类免疫缺陷病毒。如果不进行预防,艾滋病病毒MTCT的风险通常为15%-40%。MTCT导致全球约37万名婴儿感染艾滋病毒,其中尼日利亚占30%。这项研究通过审查Olabisi Onabanjo大学教学医院母婴对的健康记录来确定接受该项目的婴儿的MTCT感染率,从而评估了艾滋病毒感染MTCT预防计划的有效性。这项历时12年的横断面研究使用了545对母婴的医疗记录。在这项研究中,艾滋病病毒MTCT感染率为2.9%,而该中心早些时候报告的感染率为7.1%。在接受预防的母婴对中,艾滋病毒MTCT感染率最低。招募时的年龄是感染风险的一个重要决定因素。延迟使用MTCT预防服务是暴露婴儿感染艾滋病毒的风险。
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Evaluation of Prevention of Mother to Child Transmission Programme at a Tertiary Healthcare Facility in Southwestern Nigeria.

Most children acquire human immunodeficiency virus (HIV) infection through mother-to-child transmission (MTCT). The risk of MTCT of HIV is generally 15%-40% without prophylaxis. MTCT has been responsible for approximately 370,000 infant HIV infections worldwide, with Nigeria accounting for 30% of cases. The study evaluated the effectiveness of a prevention program for MTCT of HIV infection by determining the rate of MTCT of HIV in infants who underwent the program by reviewing health records of mother-infant pairs at the Olabisi Onabanjo University Teaching Hospital. This cross-sectional study conducted over 12 years used medical records of 545 mother-infant pairs. The rate of MTCT of HIV infection was 2.9% in this study compared to 7.1% reported by the center earlier. The rate of MTCT of HIV infection was the lowest among mother-infant pairs who received prophylaxis. Ages at recruitment are a strong determinant of the risk of infection. Late usage of the MTCT prevention service is a risk for HIV infection in exposed infants.

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来源期刊
CiteScore
4.50
自引率
4.50%
发文量
172
审稿时长
2 months
期刊介绍: Japanese Journal of Infectious Diseases (JJID), an official bimonthly publication of National Institute of Infectious Diseases, Japan, publishes papers dealing with basic research on infectious diseases relevant to humans in the fields of bacteriology, virology, mycology, parasitology, medical entomology, vaccinology, and toxinology. Pathology, immunology, biochemistry, and blood safety related to microbial pathogens are among the fields covered. Sections include: original papers, short communications, epidemiological reports, methods, laboratory and epidemiology communications, letters to the editor, and reviews.
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