高分辨率食管测压中固体餐测试的临床实用性。拉丁美洲人群研究。

K.R. García-Zermeño , J. Argüero , M. Amieva-Balmori , O. Rodríguez-Aguilera , A. Martínez-Conejo , M. Marcolongo , J.M. Remes-Troche
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引用次数: 0

摘要

简介和目的:固体试验餐(STM)是在食管测压过程中进行的一项挑战性试验,似乎可以提高研究的诊断率。我们的分析旨在确定 STM 的正常值,并评估其在一组拉丁美洲食管疾病患者和健康对照组中的临床实用性:我们对一组健康对照组和连续接受高分辨率食管测压的患者进行了横断面研究,其中 STM 在研究的最后部分进行,要求受试者吃 200 克事先煮熟的米饭。结果比较了传统方案和 STM 的结果:对 25 名对照组和 93 名患者进行了评估。大多数对照组(92%)在 8 分钟内完成了测试。在 38% 的病例中,STM 改变了测压诊断。与传统方案相比,STM 诊断出的主要运动障碍增加了 21%;食管痉挛病例增加了一倍,"千斤顶食管 "病例增加了四倍,而在之前诊断为食管运动无效的病例中,有 43% 的病例显示食管蠕动正常:我们的研究证实了这样一个事实,即与液体吞咽相比,食管测压过程中的补充性 STM 可以为食管运动障碍患者提供更多信息,对食管运动功能进行更生理学的评估。
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Clinical utility of the solid meal test during high-resolution esophageal manometry. A study in a Latin American population

Introduction and aims

The solid test meal (STM) is a challenge test that is done during esophageal manometry and appears to increase the diagnostic yield of the study. The aim of our analysis was to establish the normal values for STM and evaluate its clinical utility in a group of Latin American patients with esophageal disorders versus healthy controls.

Material and methods

A cross-sectional study was conducted on a group of healthy controls and consecutive patients that underwent high-resolution esophageal manometry, in which STM was done at the final part of the study and consisted of asking the subjects to eat 200 g of precooked rice. The results were compared during the conventional protocol and the STM.

Results

Twenty-five controls and 93 patients were evaluated. The majority of the controls (92%) completed the test in under 8 min. The STM changed the manometric diagnosis in 38% of the cases. The STM diagnosed 21% more major motor disorders than the conventional protocol; it doubled the cases of esophageal spasm and quadrupled the cases of jackhammer esophagus, whereas it demonstrated normal esophageal peristalsis in 43% of the cases with a previous diagnosis of ineffective esophageal motility.

Conclusions

Our study confirms the fact that complementary STM during esophageal manometry adds information and enables a more physiologic assessment of esophageal motor function to be made, compared with liquid swallows, in patients with esophageal motor disorders.
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