建立慢性髓性白血病患者综合护理网络:从坦桑尼亚吸取的经验教训。

IF 5 3区 医学 Q1 HEMATOLOGY Seminars in hematology Pub Date : 2023-09-01 DOI:10.1053/j.seminhematol.2023.06.002
Ahlam Nasser , Hamisa Iddy
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引用次数: 1

摘要

在过去的20年里,靶向治疗的引入和BCR::ABL1癌基因检测的进步极大地改善了慢性髓性白血病(CML)患者的综合治疗。曾经致命的恶性肿瘤现在已经转变为一种慢性疾病,患者的总体生存率接近年龄匹配的一般人群。虽然高收入国家的CML患者预后良好,但不幸的是,生活在低收入和中等收入(LMIC)国家(如坦桑尼亚)的患者预后并不相同。造成这种差异的主要原因是与提供全面护理有关的障碍,包括早期诊断、获得治疗和定期监测疾病。在这篇综述中,我们将分享我们在坦桑尼亚建立慢性粒细胞白血病患者综合护理网络的经验和教训。
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Setting up a network of comprehensive care for patients with chronic myeloid leukemia: Lessons learned from Tanzania

Over the last 2 decades, the introduction of targeted therapies and the advances in the detection of BCR::ABL1 oncogene have dramatically improved comprehensive care for patients with Chronic myeloid leukemia (CML). The once deadly malignancy has now transformed into a chronic disease with an overall patient survival approaching that of the age-matched general population. While excellent prognoses have been reported among CML patients in high-income countries, it is unfortunately not the same for those living in low and middle-income (LMIC) countries such as Tanzania. This disparity is largely contributed by barriers associated with the provision of comprehensive care including early diagnosis, access to treatment, and regular monitoring of the disease. In this review, we will share our experiences and lessons learned in setting up a network of comprehensive care for patients with CML in Tanzania.

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来源期刊
Seminars in hematology
Seminars in hematology 医学-血液学
CiteScore
6.20
自引率
2.80%
发文量
30
审稿时长
35 days
期刊介绍: Seminars in Hematology aims to present subjects of current importance in clinical hematology, including related areas of oncology, hematopathology, and blood banking. The journal''s unique issue structure allows for a multi-faceted overview of a single topic via a curated selection of review articles, while also offering a variety of articles that present dynamic and front-line material immediately influencing the field. Seminars in Hematology is devoted to making the important and current work accessible, comprehensible, and valuable to the practicing physician, young investigator, clinical practitioners, and internists/paediatricians with strong interests in blood diseases. Seminars in Hematology publishes original research, reviews, short communications and mini- reviews.
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