[睾丸网腺癌伴阴茎、肺转移1例]。

Q4 Medicine Japanese Journal of Urology Pub Date : 2022-01-01 DOI:10.5980/jpnjurol.113.78
Takeaki Noguchi, Kimito Osaka, Yousuke Shibata, Mitsuyuki Koizumi, Takahisa Suzuki, Takeshi Kishida, Youichiro Okubo, Youichi Kameda
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引用次数: 0

摘要

摘要睾丸网腺癌是一种罕见的恶性肿瘤,预后较差。我们报告一例睾丸网腺癌。一名55岁的男子感到右阴囊不适。血清标志物甲胎蛋白(AFP)、β-人绒毛膜促性腺激素(β-HCG)、LDH均为阴性。计算机断层扫描显示右侧睾丸增强。行根治性睾丸切除术。切除标本的免疫组化检查显示CEA阳性,诊断为睾丸网腺癌。血清CEA水平升高。CT显示主动脉旁淋巴结肿大。行腹膜后淋巴结清扫(RPLND),血清CEA归一化。术后4个月患者出现阴茎转移,血清CEA水平再次升高。全阴茎切除。发现肺转移和血清CEA升高后开始TIP(紫杉醇、异环磷酰胺、顺铂)治疗。TIP治疗2个周期后CT显示肺转移消失,血清CEA恢复正常。5个月后CT显示肺转移灶复发。
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[ADENOCARCINOMA OF THE RETE TESTIS WITH METASTASIS OF THE PENILE AND LUNG: A CASE REPORT].

Adenocarcinoma of the rete testis is a rare malignant tumor with poor prognosis. We report a case of adenocarcinoma of the rete testis. A 55-year-old man became aware of discomfort in the right scrotum. Negative results were obtained for the serum markers AFP, β-human chorionic gonadotropin (β-HCG), and LDH. Computed tomography (CT) showed enhancement of the right testis. Radical orchiectomy was performed. Immunohistochemical examination of the resected specimen showed positive results for CEA, and adenocarcinoma of the rete testis was diagnosed. Serum CEA level was elevated. CT showed swelling of the para-aortic lymph nodes. Retroperitoneal lymph node dissection (RPLND) was performed, and serum CEA then normalized. The patient developed penile metastases 4 months after RPLND, and serum CEA level again increased. Total penile resection was performed. TIP (Paclitaxel, Ifosfamide, Cisplatin) therapy was started after lung metastasis and increased serum CEA were identified. CT after 2 cycles of TIP therapy revealed disappearance of lung metastasis and normalization of serum CEA. Five months later, CT showed recurrence of lung metastases.

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来源期刊
Japanese Journal of Urology
Japanese Journal of Urology Medicine-Urology
CiteScore
0.20
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