缩小慢性病差距的更广泛考虑-关注心力衰竭和实施。

IF 2.4 Q2 CARDIAC & CARDIOVASCULAR SYSTEMS Current Cardiology Reviews Pub Date : 2023-01-01 DOI:10.2174/1573403X18666220512160737
Pupalan Iyngkaran, Charlotte Hespe, Fahad Hanna, John D Horowitz, Malcolm Battersby, Craig Nelson, Sharon Andrew, Maximilian P de Courten
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引用次数: 0

摘要

背景:心力衰竭(HF)主要是一种慢性疾病。HF和慢性病的研究和护理存在重叠。慢性病和HF的研究有多个目标。总体目标是“以最大的成本效益优化患者结果”。然而,对患者的观察可能有许多变量;因此,我们看到了临床翻译中的差异。本文件讨论了HF和慢性病常见的三个重要差距的论点,即筛查、自我管理和患者报告结果(PRO),并简要介绍了如何将其纳入证据树。提供了关于卫生服务框架和护理模式的相关论点,作为未来共识的前奏。方法:1)初步文献综述,以确定心血管研究的分类;2)已发表文献综述,描述将心血管疾病的研究转化为临床实践。确定了从观察性试验到大型随机对照试验再到上市后研究的范围。讨论:简要讨论传统研究和差异,重点是筛查、混合方法研究概念和慢性病护理模式。促进这一点的六个步骤:1)研究设计;2) 研究应用(翻译)一、常规二。挑战;3.将研究转化为翻译水平;4.资金和基础设施;5.卓越临床研究中心(CCRE)及其合作;6.治理和成本效益。结论:旨在以高效和有效的方式将研究结果与改善患者结果联系起来的实施研究是一个被忽视的领域。执行实施研究所需的技能是复杂的。在HF背景下描述了最大限度地将慢性病研究转化为临床实践的方法。
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The Wider Considerations in Closing Chronic Disease Gaps - Focus on Heart Failure and Implementation.

Background: Heart failure (HF) is predominately a chronic disease. There are overlaps in HF and chronic disease research and care. Chronic disease and HF research are conducted with multiple goals. The overarching goal is "optimized patient outcomes at maximum costeffectiveness". However, observations on patients can come with many variables; thus, we see differences in clinical translation. This document discusses an argument for three important gaps common to HF and chronic disease, i.e., screening, self-management, and patient-reported outcomes (PRO), and provides a glance of how it could fit into the evidence tree. Pertinent arguments for a framework for health services and models of care are provided as a prelude to future consensus.

Methodology: 1) A preliminary literature review to identify a taxonomy for cardiovascular research, and 2) a review of the published literature describing the translation of research studies into clinical practice for cardiovascular disorders. A spectrum from observational to large randomized controlled trials to post-marketing studies were identified.

Discussion: A brief discussion on traditional research and differences focusing on screening, mixed methods research concepts, and chronic diseases models of care. Six steps to facilitate this: 1) Research design; 2) Research application (translation) i. routine ii. challenges; 3. Transforming research to translational level; 4. Funding and infrastructure; 5. Clinical Centres of Research Excellence (CCRE) and collaboration; 6. Governance and cost-effectiveness.

Conclusion: Implementation research that aims to link research findings to improved patient outcomes in an efficient and effective way is a neglected area. Skills required to perform implementation research are complex. Ways to maximize translational impacts for chronic disease research to clinical practice are described in a HF context.

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来源期刊
Current Cardiology Reviews
Current Cardiology Reviews CARDIAC & CARDIOVASCULAR SYSTEMS-
CiteScore
3.70
自引率
10.50%
发文量
117
期刊介绍: Current Cardiology Reviews publishes frontier reviews of high quality on all the latest advances on the practical and clinical approach to the diagnosis and treatment of cardiovascular disease. All relevant areas are covered by the journal including arrhythmia, congestive heart failure, cardiomyopathy, congenital heart disease, drugs, methodology, pacing, and preventive cardiology. The journal is essential reading for all researchers and clinicians in cardiology.
期刊最新文献
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