欧洲分子放射性核素治疗放射生物学工作组第二次专题讨论会。

IF 9.1 1区 医学 Q1 RADIOLOGY, NUCLEAR MEDICINE & MEDICAL IMAGING Journal of Nuclear Medicine Pub Date : 2023-11-01 Epub Date: 2023-07-13 DOI:10.2967/jnumed.123.265956
Julie Nonnekens, Bart Cornelissen, Samantha Y A Terry
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引用次数: 0

摘要

分子放射性核素治疗是一种使用放射性标记的肿瘤特异性载体的相对新颖的抗癌治疗选择。在这些载体与癌症细胞结合时,放射性衰变诱导DNA损伤和其他影响,导致癌症细胞死亡。治疗方法,如神经内分泌肿瘤的[177Lu]Lu-octretate和前列腺癌症的[177Lu]Lu-PSMA,目前正在世界各地的常规临床实践中实施。尽管如此,对这些治疗方法潜在的放射生物学效应的研究对于进一步改进或开发新的治疗方法至关重要。欧洲分子放射治疗放射生物学工作组的目的是促进这一领域的知识、投资和网络。本报告总结了2023年3月13日和14日在英国伦敦举行的第二届分子放射治疗放射生物学国际研讨会上的最新研究和见解。这次专题讨论会由癌症研究英国RadNet伦敦市和欧洲分子放射治疗放射生物学工作组的成员组织。
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Second Symposium of the European Working Group on the Radiobiology of Molecular Radionuclide Therapy.

Molecular radionuclide therapy is a relatively novel anticancer treatment option using radiolabeled, tumor-specific vectors. On binding of these vectors to cancer cells, radioactive decay induces DNA damage and other effects, leading to cancer cell death. Treatments, such as with [177Lu]Lu-octreotate for neuroendocrine tumors and [177Lu]Lu-PSMA for prostate cancer, are now being implemented into routine clinical practice around the world. Nonetheless, research into the underlying radiobiologic effects of these treatments is essential to further improve them or formulate new ones. The purpose of the European Working Group on the Radiobiology of Molecular Radiotherapy is to promote knowledge, investment, and networking in this area. This report summarizes recent research and insights presented at the second International Workshop on Radiobiology of Molecular Radiotherapy, held in London, U.K., on March 13 and 14, 2023. The symposium was organized by members of the Cancer Research U.K. RadNet City of London and the European Working Group on the Radiobiology of Molecular Radiotherapy.

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来源期刊
Journal of Nuclear Medicine
Journal of Nuclear Medicine 医学-核医学
CiteScore
13.00
自引率
8.60%
发文量
340
审稿时长
1 months
期刊介绍: The Journal of Nuclear Medicine (JNM), self-published by the Society of Nuclear Medicine and Molecular Imaging (SNMMI), provides readers worldwide with clinical and basic science investigations, continuing education articles, reviews, employment opportunities, and updates on practice and research. In the 2022 Journal Citation Reports (released in June 2023), JNM ranked sixth in impact among 203 medical journals worldwide in the radiology, nuclear medicine, and medical imaging category.
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