肺栓塞与COVID-19疾病的关系

IF 0.6 4区医学 Q4 ENDOCRINOLOGY & METABOLISM Neuro endocrinology letters Pub Date : 2023-04-30

Martin Stevik, Kamil Zelenak, Anton Dzian, Beata Drobna Saniova, Zuzana Trabalkova, Daniel Lozan, Marian Grendar, Jan Sykora, Martin Vorcak, Marek Malik, Lukas Meyer, Jens Fiehler, Veronika Vajdova

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引用次数: 0

摘要

目的:本回顾性研究旨在评估COVID-19大流行期间肺栓塞与行CT肺动脉血管造影患者的人口统计学、表现症状、合并症和实验室结果的关系。方法:该研究招募了所有疑似急性肺栓塞(PE)的成年患者，这些患者在2020年3月1日至2022年4月30日SARS-CoV-2大流行期间接受了计算机断层扫描肺血管造影(CTPA)。审查了1698个ctpa并收集了各种数据。根据检查结果将患者分为4组，即PE阳性组和PE阴性组，均为COVID-19和非COVID-19患者。结果:在比较COVID-19患者和非COVID-19患者的不同预测因素时，我们注意到女性患者PE的概率较低(OR 0.77, 95% CI: 0.60-1.00, p = 0.052)，而慢性阻塞性肺疾病(COPD)患者PE的概率较低(OR 0.6, 95% CI: 0.38-0.90, p = 0.017)。较大年龄(OR 1.02, 95% CI: 1.01-1.02, p < 0.001)、心率增加(OR 1.01, 95% CI: 1.01-1.02, p < 0.001)和d -二聚体水平增加(OR 1.03, 95% CI: 1.02-1.04, p < 0.001)的患者发生PE的概率较高。结论:考虑PE的预测因素，女性和COPD的PE风险明显降低，随着年龄、心率和d -二聚体水平的增加，PE风险升高。

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Association between pulmonary embolism and COVID-19 disease.

Objectives: The current retrospective study focused on evaluation of the relationship between pulmonary embolism during COVID-19 pandemic and demographic, presenting symptoms, comorbidities and laboratory results in patients who underwent CT angiography of the pulmonary arteries.

Methods: The study enrolled all adult patients with suspected acute pulmonary embolism (PE) who underwent computed tomography pulmonary angiography (CTPA) between March 1, 2020, and April 30, 2022, during the SARS-CoV-2 pandemic. 1698 CTPAs were reviewed and various data were collected. Based on examination results, patients were divided into 4 groups: a group with positive PE and a group with negative PE for both COVID-19 and non-COVID-19 patients.

Results: When comparing different predictors of COVID-19 patients and non-COVID-19 patients we noticed lower probability of PE in female gender (OR 0.77, 95% CI: 0.60-1.00, p = 0.052) and in chronic obstructive pulmonary disease (COPD) patients (OR 0.6, 95% CI: 0.38-0.90, p = 0.017). Higher probability of PE was in cases of older age (OR 1.02, 95% CI: 1.01-1.02, p < 0.001), increased heart rate (OR 1.01, 95% CI: 1.01-1.02, p < 0.001) and increased D-dimer levels (OR 1.03, 95% CI: 1.02-1.04, p < 0.001).

Conclusion: Considering predictors of PE there was a significantly lower risk of PE in the female gender and COPD, and a higher risk with increasing age, heart rate, and D-dimer levels.

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来源期刊

Neuro endocrinology letters 医学-内分泌学与代谢

CiteScore

1.00

自引率

14.30%

发文量

审稿时长

6 months

期刊介绍： Neuroendocrinology Letters is an international, peer-reviewed interdisciplinary journal covering the fields of Neuroendocrinology, Neuroscience, Neurophysiology, Neuropsychopharmacology, Psychoneuroimmunology, Reproductive Medicine, Chronobiology, Human Ethology and related fields for RAPID publication of Original Papers, Review Articles, State-of-the-art, Clinical Reports and other contributions from all the fields covered by Neuroendocrinology Letters. Papers from both basic research (methodology, molecular and cellular biology, anatomy, histology, biology, embryology, teratology, normal and pathological physiology, biophysics, pharmacology, pathology and experimental pathology, biochemistry, neurochemistry, enzymology, chronobiology, receptor studies, endocrinology, immunology and neuroimmunology, animal physiology, animal breeding and ethology, human ethology, psychology and others) and from clinical research (neurology, psychiatry and child psychiatry, obstetrics and gynecology, pediatrics, endocrinology, immunology, cardiovascular studies, internal medicine, oncology and others) will be considered. The Journal publishes Original papers and Review Articles. Brief reports, Special Communications, proved they are based on adequate experimental evidence, Clinical Studies, Case Reports, Commentaries, Discussions, Letters to the Editor (correspondence column), Book Reviews, Congress Reports and other categories of articles (philosophy, art, social issues, medical and health policies, biomedical history, etc.) will be taken under consideration.