Nguyen Thi Cam Huong, Nguyen Van Luu, Nguyen Hai Nam, Suhaib Ghula, Ahmad Taysir Atieh Qarawi, Pham Thi Mai Truc, Dang Nguyen Trung An, Nguyen Tien Huy, Pham Thi Le Hoa
{"title":"健康检查参与者中乙型肝炎病毒感染的流行:越南胡志明市大学医学中心的一项横断面研究","authors":"Nguyen Thi Cam Huong, Nguyen Van Luu, Nguyen Hai Nam, Suhaib Ghula, Ahmad Taysir Atieh Qarawi, Pham Thi Mai Truc, Dang Nguyen Trung An, Nguyen Tien Huy, Pham Thi Le Hoa","doi":"10.1080/21548331.2023.2221132","DOIUrl":null,"url":null,"abstract":"<p><strong>Objectives: </strong>Vietnam is one of the countries in highly endemic areas of hepatitis B virus (HBV) infection in the world. Our study aims to determine the prevalence of HBV infection among different age groups of workers who had been included for annual general health checkups.</p><p><strong>Methods: </strong>This cross-sectional study was conducted at the Health Screening Department, University Medical Center at Ho Chi Minh City, Vietnam, using anonymous data from employees who had health checkups from June 2017 to June 2018.</p><p><strong>Results: </strong>A total of 5727 subjects were included, with an overall HBV prevalence of 9.0%. The prevalence of HBV infection was significantly higher in men and lowest in the age groups of 18-30. In multivariable analysis, the variables that were independently associated with HBV infection were male gender (Odd ratio (OR), 2.03; 95% confidence interval (CI), 1.58-2.60; <i>p</i> < 0.001), older than 30 years old (age group of 31-40: OR 1.7; 95% CI, 1.33-2.18; <i>p</i> < 0.001; of 41-50, OR 1.82; 95% CI, 1.37-2.43; <i>p</i> < 0.001); high total cholesterol (OR, 0.77; 95% CI, 0.64-0.94; <i>p</i> = 0.011), high triglyceride (OR, 0.53; 95% CI, 0.42-0.65; <i>p</i> < 0.001), and having significant fibrosis (OR, 2.7; 95% CI 1.85-3,95; <i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>The prevalence of HBV infection among employees on health assessments is still high (9%), even in the age group under 30 (7%). Male, age group older than 30, and significant liver fibrosis were the factors related to HBV infection. High cholesterol and level triglyceride were protective factors against HBV infection.</p>","PeriodicalId":35045,"journal":{"name":"Hospital practice (1995)","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-08-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"Prevalence of hepatitis B virus infection in health checkup participants: a cross-sectional study at University Medical Center, Ho Chi Minh City, Vietnam.\",\"authors\":\"Nguyen Thi Cam Huong, Nguyen Van Luu, Nguyen Hai Nam, Suhaib Ghula, Ahmad Taysir Atieh Qarawi, Pham Thi Mai Truc, Dang Nguyen Trung An, Nguyen Tien Huy, Pham Thi Le Hoa\",\"doi\":\"10.1080/21548331.2023.2221132\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objectives: </strong>Vietnam is one of the countries in highly endemic areas of hepatitis B virus (HBV) infection in the world. Our study aims to determine the prevalence of HBV infection among different age groups of workers who had been included for annual general health checkups.</p><p><strong>Methods: </strong>This cross-sectional study was conducted at the Health Screening Department, University Medical Center at Ho Chi Minh City, Vietnam, using anonymous data from employees who had health checkups from June 2017 to June 2018.</p><p><strong>Results: </strong>A total of 5727 subjects were included, with an overall HBV prevalence of 9.0%. The prevalence of HBV infection was significantly higher in men and lowest in the age groups of 18-30. In multivariable analysis, the variables that were independently associated with HBV infection were male gender (Odd ratio (OR), 2.03; 95% confidence interval (CI), 1.58-2.60; <i>p</i> < 0.001), older than 30 years old (age group of 31-40: OR 1.7; 95% CI, 1.33-2.18; <i>p</i> < 0.001; of 41-50, OR 1.82; 95% CI, 1.37-2.43; <i>p</i> < 0.001); high total cholesterol (OR, 0.77; 95% CI, 0.64-0.94; <i>p</i> = 0.011), high triglyceride (OR, 0.53; 95% CI, 0.42-0.65; <i>p</i> < 0.001), and having significant fibrosis (OR, 2.7; 95% CI 1.85-3,95; <i>p</i> < 0.001).</p><p><strong>Conclusions: </strong>The prevalence of HBV infection among employees on health assessments is still high (9%), even in the age group under 30 (7%). Male, age group older than 30, and significant liver fibrosis were the factors related to HBV infection. High cholesterol and level triglyceride were protective factors against HBV infection.</p>\",\"PeriodicalId\":35045,\"journal\":{\"name\":\"Hospital practice (1995)\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-08-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Hospital practice (1995)\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.1080/21548331.2023.2221132\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q2\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Hospital practice (1995)","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.1080/21548331.2023.2221132","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q2","JCRName":"Medicine","Score":null,"Total":0}
引用次数: 0
摘要
目的:越南是世界上乙型肝炎病毒(HBV)感染高发地区之一。我们的研究旨在确定每年进行一般健康检查的不同年龄组工人中HBV感染的流行情况。方法:本横断面研究在越南胡志明市大学医学中心健康筛查部进行,使用了2017年6月至2018年6月进行健康检查的员工的匿名数据。结果:共纳入5727例受试者,HBV总患病率为9.0%。乙型肝炎病毒感染率在男性中明显较高,在18-30岁年龄组中最低。在多变量分析中,与HBV感染独立相关的变量为男性(奇数比(OR), 2.03;95%置信区间(CI), 1.58-2.60;p p p p = 0.011),高甘油三酯(OR, 0.53;95% ci, 0.42-0.65;结论:健康评估的员工中HBV感染率仍然很高(9%),甚至在30岁以下的年龄组中(7%)也是如此。男性、年龄大于30岁、肝纤维化明显是HBV感染的相关因素。高胆固醇和高甘油三酯水平是预防HBV感染的保护因素。
Prevalence of hepatitis B virus infection in health checkup participants: a cross-sectional study at University Medical Center, Ho Chi Minh City, Vietnam.
Objectives: Vietnam is one of the countries in highly endemic areas of hepatitis B virus (HBV) infection in the world. Our study aims to determine the prevalence of HBV infection among different age groups of workers who had been included for annual general health checkups.
Methods: This cross-sectional study was conducted at the Health Screening Department, University Medical Center at Ho Chi Minh City, Vietnam, using anonymous data from employees who had health checkups from June 2017 to June 2018.
Results: A total of 5727 subjects were included, with an overall HBV prevalence of 9.0%. The prevalence of HBV infection was significantly higher in men and lowest in the age groups of 18-30. In multivariable analysis, the variables that were independently associated with HBV infection were male gender (Odd ratio (OR), 2.03; 95% confidence interval (CI), 1.58-2.60; p < 0.001), older than 30 years old (age group of 31-40: OR 1.7; 95% CI, 1.33-2.18; p < 0.001; of 41-50, OR 1.82; 95% CI, 1.37-2.43; p < 0.001); high total cholesterol (OR, 0.77; 95% CI, 0.64-0.94; p = 0.011), high triglyceride (OR, 0.53; 95% CI, 0.42-0.65; p < 0.001), and having significant fibrosis (OR, 2.7; 95% CI 1.85-3,95; p < 0.001).
Conclusions: The prevalence of HBV infection among employees on health assessments is still high (9%), even in the age group under 30 (7%). Male, age group older than 30, and significant liver fibrosis were the factors related to HBV infection. High cholesterol and level triglyceride were protective factors against HBV infection.