静脉镇静镇痛时使用雷马唑仑和瑞芬太尼引起严重呼吸抑制和喉痉挛1例。

IF 16.4 1区化学 Q1 CHEMISTRY, MULTIDISCIPLINARY Accounts of Chemical Research Pub Date : 2024-01-01 DOI:10.2174/1574886318666230517101142

Zhijun Xin, Ning Wang, Huaizhou Wang

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引用次数: 1

摘要

静脉镇静镇痛在小手术中应用广泛。瑞芬太尼和雷马唑仑在这种情况下是有利的，因为它们起效快，作用时间短，恢复迅速。然而，这两种药物联合需要滴定，以避免气道相关的不良事件。病例介绍:这篇文章报告了一例严重的呼吸抑制和严重的喉部痉挛，当病人接受口腔活检时，瑞芬太尼和雷马唑仑被用于镇痛和镇静。结论:本研究旨在提高麻醉医师对该类药物安全性的认识，提高麻醉医师管理该类药物使用风险的能力。

本文章由计算机程序翻译，如有差异，请以英文原文为准。

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Remimazolam and Remifentanil Use Induced Severe Respiratory Depression and Laryngeal Spasm During Intravenous Sedation and Analgesia: A Case Report.

Introduction: Intravenous sedation and analgesia are widely used in minor surgeries. Remifentanil and remimazolam are advantageous in this setting because of their rapid onset of action, and short duration of action leading to a rapid recovery. However, the two drugs combined need to be titrated to avoid airway-related adverse events.

Case presentation: This article reports a case of severe respiratory depression and severe laryngeal spasm induced by remifentanil and remimazolam when they were used for analgesia and sedation in a patient undergoing oral biopsy.

Conclusion: We aim to improve awareness about the safety of these drugs among anesthesiologists and increase their ability to manage the risk associated with their use.

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来源期刊

Accounts of Chemical Research 化学-化学综合

CiteScore

31.40

自引率

1.10%

发文量

312

审稿时长

2 months

期刊介绍： Accounts of Chemical Research presents short, concise and critical articles offering easy-to-read overviews of basic research and applications in all areas of chemistry and biochemistry. These short reviews focus on research from the author’s own laboratory and are designed to teach the reader about a research project. In addition, Accounts of Chemical Research publishes commentaries that give an informed opinion on a current research problem. Special Issues online are devoted to a single topic of unusual activity and significance. Accounts of Chemical Research replaces the traditional article abstract with an article "Conspectus." These entries synopsize the research affording the reader a closer look at the content and significance of an article. Through this provision of a more detailed description of the article contents, the Conspectus enhances the article's discoverability by search engines and the exposure for the research.