质子束治疗中闪光与照射脉冲同步1例

Takashi Saito , Masashi Mizumoto , Yoshiko Oshiro , Toshio Miyamoto , Satoshi Kamizawa , Masatoshi Nakamura , Toshiki Ishida , Hirokazu Makishima , Haruko Numajiri , Kei Nakai , Takeji Sakae , Hideyuki Sakurai
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引用次数: 0

摘要

对一位83岁鼻咽腺样囊性癌接受质子束治疗(PBT)的患者,使用事件记录仪测量脉冲束的传送时间和光闪感应时间,评估感觉光闪与质子束传送之间的相关性。治疗剂量为65 Gy (RBE),分26段2端口,两束均包括视通路(视网膜、视神经、交叉)。在26个分数中有13个得到了测量值。患者在所有13个部分中都感应到了闪光,并按下了记录按钮,430次脉冲光束输送中有426次,感应率为99.1%。按键的中位持续时间为0.3 s,与光束脉冲的中位持续时间为0.2 s基本一致,反应滞后时间为0.35 s。这些结果表明PBT期间的闪光与照射时间之间存在一致性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Synchronization of light flash with the irradiation pulse in proton beam therapy: A case report

The correlation between sensory light flash and proton beam delivery was evaluated by measuring the timing of pulse beam delivery and light flash sensing using an event recorder in an 83-year-old patient receiving proton beam therapy (PBT) for nasopharyngeal adenoid cystic carcinoma. The treatment dose was 65 Gy (RBE) in 26 fractions with 2 ports, and both beams included the visual pathway (retina, optic nerve, chiasma). Measurements were obtained in 13 of the 26 fractions. The patient sensed a light flash in all 13 fractions and pressed the recorder button for 426 of the 430 pulsed beam deliveries, giving a sensing rate of 99.1%. The median duration of button-pressing of 0.3 s was almost the same as that of the beam pulse of 0.2 s, with a reaction time lag of 0.35 s. These results suggest a consistency between light flash during PBT and the timing of irradiation.

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来源期刊
CiteScore
4.10
自引率
0.00%
发文量
48
审稿时长
67 days
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