Yu G Tikhonova, M A Kinkulkina, A V Volkov, V A Sedelkova, T I Avdeeva, T A Izyumina, M A Makarova, T N Maximova, M Yu Brovko, S V Moiseev, N N Ivanets
{"title":"[COVID-19患者谵妄的患病率及危险因素]。","authors":"Yu G Tikhonova, M A Kinkulkina, A V Volkov, V A Sedelkova, T I Avdeeva, T A Izyumina, M A Makarova, T N Maximova, M Yu Brovko, S V Moiseev, N N Ivanets","doi":"10.17116/jnevro202312307186","DOIUrl":null,"url":null,"abstract":"<p><strong>Objective: </strong>To assess the frequency and risk factors of delirium in patients hospitalized with COVID-19.</p><p><strong>Material and methods: </strong>Four hundred and forty patients admitted to the Infectious Diseases Hospital of the University Clinical Hospital No.3 of Sechenov University were included in the study. The Patient Health Questionnaire (PHQ-9), the Generalized Anxiety Disorder Screening Questionnaire-7 (GAD-7), the Insomnia Severity Index (ISI), the Delirium severity rating scale (DRS-R-98) were administered.</p><p><strong>Results: </strong>Delirium was detected in 27.8% of patients. Significant risk factors were age (<i>p</i>=0.002), severity of respiratory failure (<i>p</i>=0.005), concomitant somatic disease (<i>p</i>=0.003), and respiratory therapy (<i>p</i><0.001). There was an association between severe anxiety (<i>p</i><0.001) and insomnia (<i>p</i>=0.07) observed at admission with the risk of developing delirium during the hospital stay.</p><p><strong>Conclusion: </strong>The study reveals a high prevalence of delirium in patients with COVID-19. In order to prevent delirium and/or reduce the risk, early diagnosis and identification of preclinical forms are of particular importance.</p>","PeriodicalId":24030,"journal":{"name":"Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova","volume":null,"pages":null},"PeriodicalIF":0.0000,"publicationDate":"2023-01-01","publicationTypes":"Journal Article","fieldsOfStudy":null,"isOpenAccess":false,"openAccessPdf":"","citationCount":"0","resultStr":"{\"title\":\"[Prevalence and risk factors of delirium in COVID-19].\",\"authors\":\"Yu G Tikhonova, M A Kinkulkina, A V Volkov, V A Sedelkova, T I Avdeeva, T A Izyumina, M A Makarova, T N Maximova, M Yu Brovko, S V Moiseev, N N Ivanets\",\"doi\":\"10.17116/jnevro202312307186\",\"DOIUrl\":null,\"url\":null,\"abstract\":\"<p><strong>Objective: </strong>To assess the frequency and risk factors of delirium in patients hospitalized with COVID-19.</p><p><strong>Material and methods: </strong>Four hundred and forty patients admitted to the Infectious Diseases Hospital of the University Clinical Hospital No.3 of Sechenov University were included in the study. The Patient Health Questionnaire (PHQ-9), the Generalized Anxiety Disorder Screening Questionnaire-7 (GAD-7), the Insomnia Severity Index (ISI), the Delirium severity rating scale (DRS-R-98) were administered.</p><p><strong>Results: </strong>Delirium was detected in 27.8% of patients. Significant risk factors were age (<i>p</i>=0.002), severity of respiratory failure (<i>p</i>=0.005), concomitant somatic disease (<i>p</i>=0.003), and respiratory therapy (<i>p</i><0.001). There was an association between severe anxiety (<i>p</i><0.001) and insomnia (<i>p</i>=0.07) observed at admission with the risk of developing delirium during the hospital stay.</p><p><strong>Conclusion: </strong>The study reveals a high prevalence of delirium in patients with COVID-19. In order to prevent delirium and/or reduce the risk, early diagnosis and identification of preclinical forms are of particular importance.</p>\",\"PeriodicalId\":24030,\"journal\":{\"name\":\"Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova\",\"volume\":null,\"pages\":null},\"PeriodicalIF\":0.0000,\"publicationDate\":\"2023-01-01\",\"publicationTypes\":\"Journal Article\",\"fieldsOfStudy\":null,\"isOpenAccess\":false,\"openAccessPdf\":\"\",\"citationCount\":\"0\",\"resultStr\":null,\"platform\":\"Semanticscholar\",\"paperid\":null,\"PeriodicalName\":\"Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova\",\"FirstCategoryId\":\"1085\",\"ListUrlMain\":\"https://doi.org/10.17116/jnevro202312307186\",\"RegionNum\":0,\"RegionCategory\":null,\"ArticlePicture\":[],\"TitleCN\":null,\"AbstractTextCN\":null,\"PMCID\":null,\"EPubDate\":\"\",\"PubModel\":\"\",\"JCR\":\"Q3\",\"JCRName\":\"Medicine\",\"Score\":null,\"Total\":0}","platform":"Semanticscholar","paperid":null,"PeriodicalName":"Zhurnal nevrologii i psikhiatrii imeni S.S. Korsakova","FirstCategoryId":"1085","ListUrlMain":"https://doi.org/10.17116/jnevro202312307186","RegionNum":0,"RegionCategory":null,"ArticlePicture":[],"TitleCN":null,"AbstractTextCN":null,"PMCID":null,"EPubDate":"","PubModel":"","JCR":"Q3","JCRName":"Medicine","Score":null,"Total":0}
[Prevalence and risk factors of delirium in COVID-19].
Objective: To assess the frequency and risk factors of delirium in patients hospitalized with COVID-19.
Material and methods: Four hundred and forty patients admitted to the Infectious Diseases Hospital of the University Clinical Hospital No.3 of Sechenov University were included in the study. The Patient Health Questionnaire (PHQ-9), the Generalized Anxiety Disorder Screening Questionnaire-7 (GAD-7), the Insomnia Severity Index (ISI), the Delirium severity rating scale (DRS-R-98) were administered.
Results: Delirium was detected in 27.8% of patients. Significant risk factors were age (p=0.002), severity of respiratory failure (p=0.005), concomitant somatic disease (p=0.003), and respiratory therapy (p<0.001). There was an association between severe anxiety (p<0.001) and insomnia (p=0.07) observed at admission with the risk of developing delirium during the hospital stay.
Conclusion: The study reveals a high prevalence of delirium in patients with COVID-19. In order to prevent delirium and/or reduce the risk, early diagnosis and identification of preclinical forms are of particular importance.
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