支架辅助线圈栓塞围手术期抗血小板治疗:问卷调查结果。

Hirofumi Matsubara, Daisuke Mizutani, Yusuke Egashira, Yukiko Enomoto
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摘要

目的:本研究旨在了解日本支架辅助线圈栓塞术(SAC)围手术期抗血小板治疗的现状。方法:问卷共13个问题,采用Google表格,邮寄至有血管内专家的机构。对结果进行分析。结果:307个中心的反馈显示,半数中心在治疗前14天-1个月开始抗血小板治疗,另一半中心在治疗前7-14天开始抗血小板治疗。165个中心(56.2%)进行了血小板功能检测,其中136个中心(46.3%)对所有患者进行了这些检测,其中VerifyNow系统是使用最广泛的工具。169个中心(57.7%)、70个中心(23.5%)和42个中心(14.3%)的术后双重抗血小板治疗持续时间分别为6、3和12个月。用于单药治疗的抗血小板药物是P2Y12受体拮抗剂或阿司匹林,139个中心(47.3%)的术后时间长达12个月,68个中心(23.1%)的术后时间长达24个月,50个中心(17%)的术后时间超过24个月。结论:目前日本SAC的抗血小板治疗在各机构间差异很大。此外,每个中心都有自己的SAC经验规则。因此,本研究结果提示有必要制定SAC围手术期最佳抗血小板治疗指南。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Perioperative Antiplatelet Therapy for the Stent-Assisted Coil Embolization: Results of the Questionnaire Survey.

Objective: This study aimed to determine the status of perioperative antiplatelet therapy in stent-assisted coil embolization (SAC) in Japan.

Methods: The questionnaire consisted of 13 questions and used Google forms, and was sent to institutions where endovascular specialists were employed. The results were analyzed.

Results: The responses from 307 centers indicated that the timing of initiation of antiplatelet therapy was 14 days-1 month before treatment in half of centers, and 7-14 days before treatment in the other half. Platelet function tests were performed at 165 centers (56.2%), of which 136 centers (46.3%) performed these tests for all patients, with the VerifyNow system being the most widely used tool. The duration of postoperative dual antiplatelet therapy was 6, 3, and 12 months in 169 (57.7%), 70 (23.5%), and 42 (14.3%) centers, respectively. The antiplatelet agents used for monotherapy were P2Y12 receptor antagonists or aspirin, with a postoperative period of up to 12 months in 139 centers (47.3%), 24 months in 68 centers (23.1%), and longer than 24 months in 50 centers (17%).

Conclusion: Current antiplatelet therapy for SAC in Japan varies widely among institutions. Moreover, each center has its own empirical rules for SAC. Therefore, the findings of this survey suggest the need to establish guidelines for optimal periprocedural antiplatelet therapy for SAC.

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