[1例生殖细胞瘤化疗后腹膜后淋巴结清扫手术标本坏死组织显示hcg阳性]。

Hiromichi Sakurai, Koji Kawai, Mizuki Onozawa, Takamitsu Inoue, Jun Miyazaki
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引用次数: 0

摘要

患者为一名27岁男性。2020年12月,他被诊断为腹膜后伴下腔静脉(IVC)受累的原发性肛外生殖细胞瘤。博莱霉素、依托泊苷和顺铂治疗3个疗程后,紫杉醇、异环磷酰胺和顺铂治疗3个疗程后,血清人绒毛膜促性腺激素(hCG)水平仍然异常低。随访2个月后转介至我科。由于随访期间hCG水平持续下降,我们决定进行标记阳性手术。他接受了腹膜后淋巴结清扫术。我们还切除了部分下腔静脉壁和下腔静脉肿瘤。术后5天血清hCG水平恢复正常。病理检查仅发现坏死组织。坏死组织免疫组化示hCG阳性。
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[A Case of Germ Cell Tumor in which Necrotic Tissue Revealed hCG-Positive in Surgical Specimen of Post-Chemotherapy Retroperitoneal Lymph Node Dissection].

The patient was a 27-year-old male. In December 2020, he was diagnosed with a primary extragonadal germ cell tumor of the retroperitoneum with inferior vena caval (IVC) involvement. After 3 courses of bleomycin, etoposide and cisplatinum and 3 courses of paclitaxel, ifosfamide and cisplatin, the serum human chorionic gonadotropin (hCG) level remained abnormally low. He was referred to our department after follow-up for 2 months. Since the hCG level continued to decrease during follow-up, we decided to perform marker-positive surgery. He underwent retroperitoneal lymph node dissection. We also resected a part of the IVC wall and tumor in the IVC. The serum hCG level was normalized at 5 days after surgery. Pathological examination revealed only necrotic tissue. Immunohistochemistry showed hCG positive in the necrotic tissue.

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来源期刊
Acta Urologica Japonica
Acta Urologica Japonica Medicine-Medicine (all)
CiteScore
0.20
自引率
0.00%
发文量
74
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