虚拟阿尔茨海默病生物标志物披露的可行性:来自观察队列的发现

Pub Date : 2023-07-29 DOI:10.1002/trc2.12413
Claire M. Erickson, Nathaniel A. Chin, Hannah L. Rosario, Amanda Peterson, Sterling C. Johnson, Lindsay R. Clark
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引用次数: 1

摘要

阿尔茨海默病(AD)生物标志物测试的增加为老年人提供了寻求和了解结果的机会。我们评估了虚拟返回AD生物标志物结果的可行性。方法:训练有素的临床医生披露淀粉样正电子发射断层扫描(PET)结果,并通过电视视频向已参加AD研究的认知功能正常的参与者提供痴呆风险降低咨询(n = 99;平均年龄±SD: 72.0±4.8;67%的女性;95%的白人;淀粉样蛋白升高28%)。结果我们的研究显示了可接受的保留率(93%)、依从性(98%)、依从性(98%)、临床医生能力(97%)、教育理解(测验得分14/15)和虚拟就诊功能(评分9.4/10)。抑郁、焦虑和自杀倾向仍然很低,且淀粉样蛋白结果没有差异。淀粉样蛋白PET结果对认知未受损的研究参与者的虚拟返回是可行的,并且不会导致心理症状的增加。一些参与者面临的技术障碍突出了灵活性的必要性。这些发现支持在AD生物标志物披露中使用电视,尽管我们的研究样本和设计在推广方面存在重要的局限性。
本文章由计算机程序翻译,如有差异,请以英文原文为准。

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Feasibility of virtual Alzheimer's biomarker disclosure: Findings from an observational cohort
Increased availability of Alzheimer's disease (AD) biomarker tests provides older adults with opportunities to seek out and learn results. We evaluated the feasibility of virtually returning AD biomarker results.
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